GO Annotations Graph

• Symbol: Ddr1
• Name: discoidin domain receptor family, member 1
• ID: MGI:99216

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005518	collagen binding	IMP	J:109760
Molecular Function	GO:0005518	collagen binding	ISO	J:164563
Molecular Function	GO:0005518	collagen binding	IBA	J:265628
Molecular Function	GO:0005518	collagen binding	IDA	J:111768
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:60000
Molecular Function	GO:0038062	protein tyrosine kinase collagen receptor activity	ISO	J:164563
Molecular Function	GO:0038062	protein tyrosine kinase collagen receptor activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEA	J:72245
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEA	J:72247
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0005903	brush border	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IDA	J:103387
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0061564	axon development	IMP	J:64375
Biological Process	GO:0060444	branching involved in mammary gland duct morphogenesis	IMP	J:68368
Biological Process	GO:0008283	cell population proliferation	IMP	J:103387
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	IMP	J:109760
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	ISO	J:164563
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	IDA	J:64375
Biological Process	GO:0043583	ear development	IMP	J:68368
Biological Process	GO:0007566	embryo implantation	IMP	J:68368
Biological Process	GO:0007565	female pregnancy	IEA	J:60000
Biological Process	GO:0007595	lactation	IEA	J:60000
Biological Process	GO:0060749	mammary gland alveolus development	IMP	J:68368
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:103387
Biological Process	GO:1990138	neuron projection extension	IMP	J:64375
Biological Process	GO:0038083	peptidyl-tyrosine autophosphorylation	ISO	J:164563
Biological Process	GO:0038083	peptidyl-tyrosine autophosphorylation	IDA	J:64375
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IDA	J:103387
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0010976	positive regulation of neuron projection development	IBA	J:265628
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	IBA	J:265628
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:64375
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0001558	regulation of cell growth	IMP	J:103387
Biological Process	GO:0001952	regulation of cell-matrix adhesion	IMP	J:103387
Biological Process	GO:0010715	regulation of extracellular matrix disassembly	ISO	J:164563
Biological Process	GO:0010715	regulation of extracellular matrix disassembly	IMP	J:109760
Biological Process	GO:0014909	smooth muscle cell migration	IMP	J:109760
Biological Process	GO:0014909	smooth muscle cell migration	ISO	J:164563
Biological Process	GO:0061302	smooth muscle cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0061302	smooth muscle cell-matrix adhesion	IMP	J:109760
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628
Biological Process	GO:0044319	wound healing, spreading of cells	IMP	J:109760
Biological Process	GO:0044319	wound healing, spreading of cells	ISO	J:164563