GO Annotations Graph

• Symbol: Shb
• Name: src homology 2 domain-containing transforming protein B
• ID: MGI:98294

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001784	phosphotyrosine residue binding	ISO	J:164563
Molecular Function	GO:0001784	phosphotyrosine residue binding	IBA	J:265628
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	IDA	J:16321
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0042100	B cell proliferation	IDA	J:74310
Biological Process	GO:0001568	blood vessel development	IMP	J:146611
Biological Process	GO:0048514	blood vessel morphogenesis	IGI	J:100933
Biological Process	GO:0048514	blood vessel morphogenesis	IMP	J:100933
Biological Process	GO:0048514	blood vessel morphogenesis	IGI	J:100933
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071425	hematopoietic stem cell proliferation	IMP	J:203580
Biological Process	GO:0030097	hemopoiesis	IMP	J:117357
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1900194	negative regulation of oocyte maturation	IMP	J:162014
Biological Process	GO:0006469	negative regulation of protein kinase activity	IMP	J:203580
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	IMP	J:203580
Biological Process	GO:0045624	positive regulation of T-helper cell differentiation	IMP	J:218575
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:218575