GO Annotations Graph

• Symbol: Rdx
• Name: radixin
• ID: MGI:97887

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:155856
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0003779	actin binding	IBA	J:265628
Molecular Function	GO:0051117	ATPase binding	ISO	J:164563
Molecular Function	GO:0050839	cell adhesion molecule binding	IBA	J:265628
Molecular Function	GO:0008092	cytoskeletal protein binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:116255
Molecular Function	GO:0005515	protein binding	IPI	J:255604
Molecular Function	GO:0005515	protein binding	IPI	J:177167
Molecular Function	GO:0005515	protein binding	IPI	J:247408
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0005515	protein binding	IPI	J:77485
Molecular Function	GO:0005515	protein binding	IPI	J:77485
Molecular Function	GO:0005515	protein binding	IPI	J:77485
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:222678
Molecular Function	GO:0051018	protein kinase A binding	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0045177	apical part of cell	IBA	J:265628
Cellular Component	GO:0045177	apical part of cell	IDA	J:52936
Cellular Component	GO:0045177	apical part of cell	IDA	J:52936
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0071944	cell periphery	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0051286	cell tip	ISO	J:155856
Cellular Component	GO:0032154	cleavage furrow	ISO	J:155856
Cellular Component	GO:0030864	cortical actin cytoskeleton	IDA	J:222678
Cellular Component	GO:0030864	cortical actin cytoskeleton	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:72247
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0030175	filopodium	ISO	J:155856
Cellular Component	GO:0030175	filopodium	IDA	J:222678
Cellular Component	GO:0030175	filopodium	IBA	J:265628
Cellular Component	GO:0030175	filopodium	IDA	J:46918
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	IDA	J:222678
Cellular Component	GO:0030027	lamellipodium	IDA	J:46918
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005902	microvillus	IDA	J:255604
Cellular Component	GO:0005902	microvillus	IDA	J:222678
Cellular Component	GO:0005902	microvillus	ISO	J:155856
Cellular Component	GO:0005902	microvillus	IBA	J:265628
Cellular Component	GO:0005902	microvillus	IDA	J:77485
Cellular Component	GO:0005902	microvillus	IDA	J:89351
Cellular Component	GO:0030496	midbody	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:222678
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0001726	ruffle	IDA	J:46918
Cellular Component	GO:0032420	stereocilium	IDA	J:112741
Cellular Component	GO:0032420	stereocilium	IDA	J:112741
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Biological Process	GO:0051693	actin filament capping	IEA	J:60000
Biological Process	GO:0045176	apical protein localization	ISO	J:155856
Biological Process	GO:0045176	apical protein localization	IMP	J:77485
Biological Process	GO:0051016	barbed-end actin filament capping	ISO	J:155856
Biological Process	GO:0097067	cellular response to thyroid hormone stimulus	IMP	J:222678
Biological Process	GO:0097067	cellular response to thyroid hormone stimulus	ISO	J:155856
Biological Process	GO:0061028	establishment of endothelial barrier	ISO	J:164563
Biological Process	GO:0045184	establishment of protein localization	IMP	J:222678
Biological Process	GO:0061951	establishment of protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:0030033	microvillus assembly	IMP	J:77485
Biological Process	GO:1903392	negative regulation of adherens junction organization	ISO	J:164563
Biological Process	GO:0045792	negative regulation of cell size	ISO	J:164563
Biological Process	GO:0034260	negative regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0034111	negative regulation of homotypic cell-cell adhesion	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:2000643	positive regulation of early endosome to late endosome transport	ISO	J:164563
Biological Process	GO:2000643	positive regulation of early endosome to late endosome transport	IBA	J:265628
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	IMP	J:222678
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0045732	positive regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:1902966	positive regulation of protein localization to early endosome	ISO	J:164563
Biological Process	GO:1902966	positive regulation of protein localization to early endosome	IBA	J:265628
Biological Process	GO:0010737	protein kinase A signaling	ISO	J:155856
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0032231	regulation of actin filament bundle assembly	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	IBA	J:265628
Biological Process	GO:0008361	regulation of cell size	ISO	J:164563
Biological Process	GO:0043087	regulation of GTPase activity	ISO	J:164563
Biological Process	GO:1902115	regulation of organelle assembly	ISO	J:164563
Biological Process	GO:1902115	regulation of organelle assembly	IBA	J:265628
Biological Process	GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	IDA	J:222705
Biological Process	GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	IDA	J:222705
Biological Process	GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	IMP	J:222705
Biological Process	GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	IDA	J:222705
Biological Process	GO:0032487	regulation of Rap protein signal transduction	ISO	J:155856
Biological Process	GO:1900027	regulation of ruffle assembly	ISO	J:164563