Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables protein domain specific binding activity. Involved in several processes, including cellular response to thyroid hormone stimulus; positive regulation of G1/S transition of mitotic cell cycle; and regulation of postsynaptic neurotransmitter receptor diffusion trapping. Acts upstream of or within apical protein localization and microvillus assembly. Located in several cellular components, including lamellipodium; ruffle; and stereocilium base. Colocalizes with plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and sensory organ. Used to study Dubin-Johnson syndrome. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 24. Orthologous to human RDX (radixin).