GO Annotations Graph

• Symbol: Plg
• Name: plasminogen
• ID: MGI:97620

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0034185	apolipoprotein binding	ISO	J:164563
Molecular Function	GO:0004175	endopeptidase activity	ISO	J:155856
Molecular Function	GO:0004175	endopeptidase activity	ISO	J:164563
Molecular Function	GO:0004175	endopeptidase activity	IBA	J:265628
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0019900	kinase binding	IPI	J:240586
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:1990405	protein antigen binding	ISO	J:164563
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:164563
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0008236	serine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:149113
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2533953
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0019897	extrinsic component of plasma membrane	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105428
Cellular Component	GO:0098978	glutamatergic synapse	IEP	J:105428
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105428
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:105428
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105428
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:105428
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:105428
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IEP	J:105428
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:105428
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:105428
Cellular Component	GO:0045202	synapse	IMP	J:105428
Biological Process	GO:0051702	biological process involved in interaction with symbiont	ISO	J:164563
Biological Process	GO:0007596	blood coagulation	ISO	J:164563
Biological Process	GO:0022617	extracellular matrix disassembly	ISO	J:164563
Biological Process	GO:0042730	fibrinolysis	ISO	J:164563
Biological Process	GO:0007599	hemostasis	IEA	J:60000
Biological Process	GO:0060716	labyrinthine layer blood vessel development	IMP	J:84595
Biological Process	GO:0071674	mononuclear cell migration	IMP	J:149113
Biological Process	GO:0046716	muscle cell cellular homeostasis	IMP	J:76082
Biological Process	GO:0045445	myoblast differentiation	IMP	J:76082
Biological Process	GO:0016525	negative regulation of angiogenesis	TAS	J:78784
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	ISO	J:164563
Biological Process	GO:0051918	negative regulation of fibrinolysis	ISO	J:164563
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	ISO	J:164563
Biological Process	GO:0051919	positive regulation of fibrinolysis	ISO	J:164563
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IBA	J:265628
Biological Process	GO:0051603	proteolysis involved in protein catabolic process	ISO	J:155856
Biological Process	GO:0042246	tissue regeneration	IMP	J:76082
Biological Process	GO:0048771	tissue remodeling	IEA	J:60000
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	IDA	J:105428
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	IMP	J:105428
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	IEP	J:105428
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	IDA	J:105428
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	IMP	J:105428
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	IEP	J:105428
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	IDA	J:105428
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	IDA	J:105428
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	IDA	J:105428
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	IDA	J:105428
Biological Process	GO:0060707	trophoblast giant cell differentiation	IMP	J:84595