Automated description from the Alliance of Genome Resources (Release 5.4.0)
Enables kinase binding activity. Involved in trans-synaptic signaling by BDNF, modulating synaptic transmission. Acts upstream of or within several processes, including embryonic placenta development; muscle cell cellular homeostasis; and myoblast differentiation. Located in cell surface and synapse. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in early conceptus; embryo; liver; and secondary oocyte. Human ortholog(s) of this gene implicated in COVID-19; conjunctivitis; hereditary angioedema; plasminogen deficiency type I; and thrombophilia. Orthologous to human PLG (plasminogen).