GO Annotations Graph

• Symbol: Prkcb
• Name: protein kinase C, beta
• ID: MGI:97596

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005246	calcium channel regulator activity	IDA	J:75871
Molecular Function	GO:0004698	calcium-dependent protein kinase C activity	IEA	J:72245
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0035403	histone H3T6 kinase activity	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0050681	nuclear androgen receptor binding	ISO	J:164563
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:201418
Molecular Function	GO:0005515	protein binding	IPI	J:117440
Molecular Function	GO:0005515	protein binding	IPI	J:173559
Molecular Function	GO:0005515	protein binding	IPI	J:127950
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004697	protein kinase C activity	ISO	J:164563
Molecular Function	GO:0004697	protein kinase C activity	ISO	J:155856
Molecular Function	GO:0004697	protein kinase C activity	IDA	J:328025
Molecular Function	GO:0004697	protein kinase C activity	IDA	J:94466
Molecular Function	GO:0004697	protein kinase C activity	IDA	J:82431
Molecular Function	GO:0005080	protein kinase C binding	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:204720
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0031526	brush border membrane	ISO	J:155856
Cellular Component	GO:0044305	calyx of Held	IC	J:174964
Cellular Component	GO:0044305	calyx of Held	IDA	J:174964
Cellular Component	GO:0044305	calyx of Held	IDA	J:174964
Cellular Component	GO:0044305	calyx of Held	IDA	J:174964
Cellular Component	GO:0044305	calyx of Held	IMP	J:174964
Cellular Component	GO:0005813	centrosome	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:85668
Cellular Component	GO:0005737	cytoplasm	IDA	J:87315
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:87315
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:328025
Cellular Component	GO:0098793	presynapse	IMP	J:174964
Cellular Component	GO:0099523	presynaptic cytosol	IDA	J:174964
Cellular Component	GO:0099523	presynaptic cytosol	IDA	J:174964
Cellular Component	GO:0008091	spectrin	IDA	J:58132
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0042113	B cell activation	IMP	J:109151
Biological Process	GO:0050853	B cell receptor signaling pathway	IMP	J:109151
Biological Process	GO:0006816	calcium ion transport	IDA	J:75871
Biological Process	GO:0071322	cellular response to carbohydrate stimulus	IDA	J:121666
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IDA	J:75871
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:0010829	negative regulation of glucose transmembrane transport	IMP	J:108802
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	ISO	J:155856
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0007207	phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	IDA	J:328025
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0045766	positive regulation of angiogenesis	IMP	J:73979
Biological Process	GO:0050861	positive regulation of B cell receptor signaling pathway	IMP	J:118843
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:109151
Biological Process	GO:0032024	positive regulation of insulin secretion	IDA	J:328025
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IMP	J:118843
Biological Process	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	IMP	J:73979
Biological Process	GO:0043687	post-translational protein modification	ISO	J:164563
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:174964
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:174964
Biological Process	GO:0006468	protein phosphorylation	IDA	J:82431
Biological Process	GO:0006468	protein phosphorylation	IDA	J:94466
Biological Process	GO:0014059	regulation of dopamine secretion	ISO	J:155856
Biological Process	GO:0010827	regulation of glucose transmembrane transport	ISO	J:164563
Biological Process	GO:0040008	regulation of growth	ISO	J:155856
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IMP	J:174964
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IDA	J:174964
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856