Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables calcium channel regulator activity and diacylglycerol-dependent serine/threonine kinase activity. Involved in several processes, including modulation of chemical synaptic transmission; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway; and positive regulation of cell communication. Acts upstream of or within calcium ion transport; cellular response to carbohydrate stimulus; and intracellular calcium ion homeostasis. Located in cytoplasm and nucleus. Part of spectrin. Is active in calyx of Held; plasma membrane; and presynaptic cytosol. Is expressed in several structures, including central nervous system; exocrine system; genitourinary system; heart ventricle; and retina. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and lung non-small cell carcinoma. Orthologous to human PRKCB (protein kinase C beta).