Pbx1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Pbx1
pre B cell leukemia homeobox 1
MGI:97495

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:42999
Molecular Function	GO:0003677	DNA binding	ISO	J:80127
Molecular Function	GO:0003677	DNA binding	IDA	J:45106
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:211245
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:184521
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:295468
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:305429
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:245314
Molecular Function	GO:0005515	protein binding	IPI	J:160776
Molecular Function	GO:0005515	protein binding	IPI	J:89598
Molecular Function	GO:0005515	protein binding	IPI	J:89598
Molecular Function	GO:0005515	protein binding	IPI	J:45106
Molecular Function	GO:0005515	protein binding	IPI	J:42999
Molecular Function	GO:0005515	protein binding	IPI	J:89598
Molecular Function	GO:0005515	protein binding	IPI	J:99062
Molecular Function	GO:0005515	protein binding	IPI	J:56023
Molecular Function	GO:0005515	protein binding	IPI	J:89598
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:211245
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:89598
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:99062
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:295468
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:111418
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:119671
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:119671
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:141247
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:119671
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:119671
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:95309
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Molecular Function	GO:0001222	transcription corepressor binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:89962
Cellular Component	GO:0005737	cytoplasm	IDA	J:83331
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619424
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621004
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621012
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5693628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:295468
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:71996
Cellular Component	GO:0005634	nucleus	IDA	J:89962
Cellular Component	GO:0005634	nucleus	IDA	J:75811
Cellular Component	GO:0005634	nucleus	IDA	J:42999
Cellular Component	GO:0005634	nucleus	IDA	J:71996
Cellular Component	GO:0005634	nucleus	IDA	J:65141
Cellular Component	GO:0005634	nucleus	IDA	J:71996
Cellular Component	GO:0005634	nucleus	IDA	J:83331
Cellular Component	GO:0005634	nucleus	IDA	J:63180
Cellular Component	GO:0005634	nucleus	IDA	J:71996
Cellular Component	GO:0005634	nucleus	IDA	J:95019
Cellular Component	GO:0005634	nucleus	IDA	J:71996
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:56023
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:119671
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:89598
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:45106
Biological Process	GO:0030325	adrenal gland development	IMP	J:87270
Biological Process	GO:0009887	animal organ morphogenesis	IBA	J:265628
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:75811
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:71996
Biological Process	GO:0007420	brain development	IBA	J:265628
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IDA	J:82126
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0008283	cell population proliferation	IMP	J:184521
Biological Process	GO:0008283	cell population proliferation	IMP	J:99062
Biological Process	GO:0035162	embryonic hemopoiesis	IMP	J:70684
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:109528
Biological Process	GO:0048568	embryonic organ development	IBA	J:265628
Biological Process	GO:0048568	embryonic organ development	IMP	J:95019
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:71996
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:71996
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:71996
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:71996
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:71996
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:71996
Biological Process	GO:0001654	eye development	IBA	J:265628
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	IMP	J:184521
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	IMP	J:184521
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0001779	natural killer cell differentiation	IMP	J:295468
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0045665	negative regulation of neuron differentiation	IGI	J:131060
Biological Process	GO:0045665	negative regulation of neuron differentiation	IGI	J:131060
Biological Process	GO:0048666	neuron development	IBA	J:265628
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	IMP	J:184521
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IMP	J:99062
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IMP	J:184521
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:295468
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:211245
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:99062
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:141247
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:71996
Biological Process	GO:0009954	proximal/distal pattern formation	IGI	J:109528
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:71996
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:71996
Biological Process	GO:0009954	proximal/distal pattern formation	IGI	J:109528
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:71996
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:71996
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0030278	regulation of ossification	IMP	J:71996
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0007548	sex differentiation	IEA	J:60000
Biological Process	GO:0048536	spleen development	IMP	J:99062
Biological Process	GO:0048536	spleen development	IGI	J:184521
Biological Process	GO:0048536	spleen development	IGI	J:184521
Biological Process	GO:0048536	spleen development	IGI	J:99062
Biological Process	GO:0072089	stem cell proliferation	IMP	J:184521
Biological Process	GO:0072089	stem cell proliferation	IMP	J:99062
Biological Process	GO:0006694	steroid biosynthetic process	IEA	J:60000
Biological Process	GO:0048538	thymus development	IMP	J:95019
Biological Process	GO:0001655	urogenital system development	IMP	J:87270

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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