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GO Annotations Graph
Symbol
Name
ID
Kdr
kinase insert domain protein receptor
MGI:96683

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0019838growth factor bindingISOJ:164563
Molecular FunctionGO:0019838growth factor bindingIPIJ:36300
Molecular FunctionGO:0019838growth factor bindingIPIJ:63336
Molecular FunctionGO:0019838growth factor bindingISOJ:155856
Molecular FunctionGO:0005178integrin bindingISOJ:164563
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:88810
Molecular FunctionGO:0005515protein bindingIPIJ:200377
Molecular FunctionGO:0005515protein bindingIPIJ:190412
Molecular FunctionGO:0005515protein bindingIPIJ:159519
Molecular FunctionGO:0005515protein bindingIPIJ:203489
Molecular FunctionGO:0005515protein bindingIPIJ:166472
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72247
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72245
Molecular FunctionGO:0038085vascular endothelial growth factor bindingISOJ:164563
Molecular FunctionGO:0005021vascular endothelial growth factor-activated receptor activityISOJ:155856
Molecular FunctionGO:0005021vascular endothelial growth factor-activated receptor activityISOJ:164563
Molecular FunctionGO:0005021vascular endothelial growth factor-activated receptor activityIDAJ:91451
Cellular ComponentGO:0030054cell junctionIDAJ:152727
Cellular ComponentGO:0071944cell peripheryIDAJ:104149
Cellular ComponentGO:0009986cell surfaceIDAJ:190263
Cellular ComponentGO:0005737cytoplasmIDAJ:191431
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0031410cytoplasmic vesicleIEAJ:60000
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0005769early endosomeIDAJ:166472
Cellular ComponentGO:0005769early endosomeIDAJ:197143
Cellular ComponentGO:0005783endoplasmic reticulumISOJ:164563
Cellular ComponentGO:0005768endosomeISOJ:164563
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:132871
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:160232
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:155850
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005794Golgi apparatusISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0005887integral component of plasma membraneISOJ:164563
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0045121membrane raftISOJ:164563
Cellular ComponentGO:0043005neuron projectionISOJ:155856
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:191431
Cellular ComponentGO:0005886plasma membraneIDAJ:166472
Cellular ComponentGO:0005886plasma membraneIDAJ:197143
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0097443sorting endosomeIDAJ:197143
Biological ProcessGO:0001525angiogenesisIEAJ:60000
Biological ProcessGO:0060837blood vessel endothelial cell differentiationTASJ:164086
Biological ProcessGO:0048754branching morphogenesis of an epithelial tubeIMPJ:104895
Biological ProcessGO:0055074calcium ion homeostasisIDAJ:91451
Biological ProcessGO:0035584calcium-mediated signaling using intracellular calcium sourceISOJ:164563
Biological ProcessGO:0030154cell differentiationIEAJ:60000
Biological ProcessGO:0045165cell fate commitmentIMPJ:81796
Biological ProcessGO:0048469cell maturationIMPJ:77480
Biological ProcessGO:0016477cell migrationIGIJ:95386
Biological ProcessGO:0002042cell migration involved in sprouting angiogenesisIMPJ:166472
Biological ProcessGO:0035924cellular response to vascular endothelial growth factor stimulusISOJ:164563
Biological ProcessGO:0035162embryonic hemopoiesisIMPJ:26846
Biological ProcessGO:0003157endocardium developmentIMPJ:26846
Biological ProcessGO:0003416endochondral bone growthISOJ:155856
Biological ProcessGO:0045446endothelial cell differentiationIDAJ:84798
Biological ProcessGO:0045446endothelial cell differentiationTASJ:164086
Biological ProcessGO:0003158endothelium developmentIMPJ:26846
Biological ProcessGO:0030097hemopoiesisIMPJ:96124
Biological ProcessGO:0048286lung alveolus developmentIMPJ:77480
Biological ProcessGO:0030324lung developmentIMPJ:104895
Biological ProcessGO:0001945lymph vessel developmentIGIJ:159519
Biological ProcessGO:0008584male gonad developmentISOJ:155856
Biological ProcessGO:0007275multicellular organism developmentIEAJ:60000
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:164563
Biological ProcessGO:2000352negative regulation of endothelial cell apoptotic processISOJ:164563
Biological ProcessGO:0043524negative regulation of neuron apoptotic processISOJ:155856
Biological ProcessGO:0048812neuron projection morphogenesisISOJ:155856
Biological ProcessGO:0001541ovarian follicle developmentIMPJ:121170
Biological ProcessGO:0038083peptidyl-tyrosine autophosphorylationIDAJ:166472
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0045766positive regulation of angiogenesisISOJ:164563
Biological ProcessGO:0045766positive regulation of angiogenesisIDAJ:164086
Biological ProcessGO:0045766positive regulation of angiogenesisISOJ:155856
Biological ProcessGO:0030513positive regulation of BMP signaling pathwayIDAJ:164086
Biological ProcessGO:0050850positive regulation of calcium-mediated signalingISOJ:155856
Biological ProcessGO:0030335positive regulation of cell migrationISOJ:164563
Biological ProcessGO:0030335positive regulation of cell migrationISOJ:155856
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:155856
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:164563
Biological ProcessGO:0007204positive regulation of cytosolic calcium ion concentrationISOJ:155856
Biological ProcessGO:0038033positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathwayISOJ:164563
Biological ProcessGO:0010595positive regulation of endothelial cell migrationISOJ:164563
Biological ProcessGO:0010595positive regulation of endothelial cell migrationTASJ:164086
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationISOJ:155856
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationISOJ:164563
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationIMPJ:104895
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0051894positive regulation of focal adhesion assemblyISOJ:164563
Biological ProcessGO:0048170positive regulation of long-term neuronal synaptic plasticityISOJ:155856
Biological ProcessGO:0016239positive regulation of macroautophagyISOJ:73065
Biological ProcessGO:0043410positive regulation of MAPK cascadeISOJ:164563
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationIMPJ:104895
Biological ProcessGO:0051901positive regulation of mitochondrial depolarizationISOJ:73065
Biological ProcessGO:0090141positive regulation of mitochondrial fissionISOJ:73065
Biological ProcessGO:0051770positive regulation of nitric-oxide synthase biosynthetic processISOJ:164563
Biological ProcessGO:0014068positive regulation of phosphatidylinositol 3-kinase signalingISOJ:155856
Biological ProcessGO:0014068positive regulation of phosphatidylinositol 3-kinase signalingISOJ:164563
Biological ProcessGO:0050927positive regulation of positive chemotaxisISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:0032008positive regulation of TOR signalingISOJ:155856
Biological ProcessGO:0030949positive regulation of vascular endothelial growth factor receptor signaling pathwayTASJ:164086
Biological ProcessGO:2001214positive regulation of vasculogenesisIMPJ:152727
Biological ProcessGO:0045909positive regulation of vasodilationISOJ:155856
Biological ProcessGO:0048597post-embryonic camera-type eye morphogenesisIGIJ:183383
Biological ProcessGO:0046777protein autophosphorylationISOJ:164563
Biological ProcessGO:0046777protein autophosphorylationISOJ:155856
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:1903010regulation of bone developmentIMPJ:191431
Biological ProcessGO:0008360regulation of cell shapeISOJ:164563
Biological ProcessGO:0045601regulation of endothelial cell differentiationIMPJ:204805
Biological ProcessGO:0001936regulation of endothelial cell proliferationTASJ:164086
Biological ProcessGO:1901532regulation of hematopoietic progenitor cell differentiationIMPJ:204805
Biological ProcessGO:0042493response to drugISOJ:155856
Biological ProcessGO:0001666response to hypoxiaISOJ:155856
Biological ProcessGO:0043129surfactant homeostasisIMPJ:77480
Biological ProcessGO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayIEAJ:72247
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayIDAJ:91451
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayISOJ:164563
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayISOJ:155856
Biological ProcessGO:0038084vascular endothelial growth factor signaling pathwayISOJ:155856
Biological ProcessGO:0001570vasculogenesisIMPJ:26846
Biological ProcessGO:0001570vasculogenesisIMPJ:96124


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory