GO Annotations Graph

• Symbol: Smarca4
• Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
• ID: MGI:88192

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016887	ATP hydrolysis activity	TAS	J:66861
Molecular Function	GO:0016887	ATP hydrolysis activity	IMP	J:184001
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	ISO	J:164563
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	IBA	J:265628
Molecular Function	GO:0140658	ATP-dependent chromatin remodeler activity	IDA	J:321533
Molecular Function	GO:0003682	chromatin binding	IDA	J:230626
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0003682	chromatin binding	IDA	J:213053
Molecular Function	GO:0003682	chromatin binding	IDA	J:117710
Molecular Function	GO:0003682	chromatin binding	IDA	J:104088
Molecular Function	GO:0003682	chromatin binding	IDA	J:132583
Molecular Function	GO:0003682	chromatin binding	IDA	J:55698
Molecular Function	GO:0003682	chromatin binding	IDA	J:103896
Molecular Function	GO:0003677	DNA binding	IBA	J:265628
Molecular Function	GO:0070182	DNA polymerase binding	ISO	J:164563
Molecular Function	GO:0070182	DNA polymerase binding	IPI	J:150343
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0042393	histone binding	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0106222	lncRNA binding	IPI	J:213053
Molecular Function	GO:0070577	lysine-acetylated histone binding	ISO	J:164563
Molecular Function	GO:0050681	nuclear androgen receptor binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:162637
Molecular Function	GO:0005515	protein binding	IPI	J:118741
Molecular Function	GO:0005515	protein binding	IPI	J:180159
Molecular Function	GO:0005515	protein binding	IPI	J:139425
Molecular Function	GO:0005515	protein binding	IPI	J:198738
Molecular Function	GO:0005515	protein binding	IPI	J:204641
Molecular Function	GO:0005515	protein binding	IPI	J:168216
Molecular Function	GO:0005515	protein binding	IPI	J:222133
Molecular Function	GO:0005515	protein binding	IPI	J:239191
Molecular Function	GO:0005515	protein binding	IPI	J:291869
Molecular Function	GO:0005515	protein binding	IPI	J:182409
Molecular Function	GO:0005515	protein binding	IPI	J:321533
Molecular Function	GO:0005515	protein binding	IPI	J:248235
Molecular Function	GO:0005515	protein binding	IPI	J:304578
Molecular Function	GO:0005515	protein binding	IPI	J:150343
Molecular Function	GO:0005515	protein binding	IPI	J:198738
Molecular Function	GO:0005515	protein binding	IPI	J:166998
Molecular Function	GO:0005515	protein binding	IPI	J:132090
Molecular Function	GO:0005515	protein binding	IPI	J:197250
Molecular Function	GO:0005515	protein binding	IPI	J:306579
Molecular Function	GO:0005515	protein binding	IPI	J:104088
Molecular Function	GO:0005515	protein binding	IPI	J:37212
Molecular Function	GO:0005515	protein binding	IPI	J:172496
Molecular Function	GO:0005515	protein binding	IPI	J:201868
Molecular Function	GO:0005515	protein binding	IPI	J:103896
Molecular Function	GO:0005515	protein binding	IPI	J:84944
Molecular Function	GO:0005515	protein binding	IPI	J:182882
Molecular Function	GO:0005515	protein binding	IPI	J:181256
Molecular Function	GO:0005515	protein binding	IPI	J:103896
Molecular Function	GO:0005515	protein binding	IPI	J:172496
Molecular Function	GO:0005515	protein binding	IPI	J:104088
Molecular Function	GO:0005515	protein binding	IPI	J:156242
Molecular Function	GO:0005515	protein binding	IPI	J:103896
Molecular Function	GO:0005515	protein binding	IPI	J:180125
Molecular Function	GO:0005515	protein binding	IPI	J:184001
Molecular Function	GO:0005515	protein binding	IPI	J:117710
Molecular Function	GO:0005515	protein binding	IPI	J:193698
Molecular Function	GO:0005515	protein binding	IPI	J:184001
Molecular Function	GO:0005515	protein binding	IPI	J:103896
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:193698
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:160495
Molecular Function	GO:0030957	Tat protein binding	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0008134	transcription factor binding	IBA	J:265628
Molecular Function	GO:0008134	transcription factor binding	IPI	J:97581
Cellular Component	GO:0140092	bBAF complex	NAS	J:156242
Cellular Component	GO:0000785	chromatin	NAS	J:283189
Cellular Component	GO:0000785	chromatin	NAS	J:320042
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0000791	euchromatin	IDA	J:55698
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0140288	GBAF complex	NAS	J:283189
Cellular Component	GO:0000792	heterochromatin	IDA	J:104088
Cellular Component	GO:0000776	kinetochore	NAS	J:320056
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:112036
Cellular Component	GO:0071565	nBAF complex	NAS	J:132101
Cellular Component	GO:0071565	nBAF complex	IDA	J:132090
Cellular Component	GO:0071565	nBAF complex	IDA	J:199644
Cellular Component	GO:0071564	npBAF complex	NAS	J:35263
Cellular Component	GO:0071564	npBAF complex	ISO	J:164563
Cellular Component	GO:0071564	npBAF complex	IDA	J:132090
Cellular Component	GO:0071564	npBAF complex	IDA	J:199644
Cellular Component	GO:0016363	nuclear matrix	NAS	J:320261
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:239652
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:204641
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:321533
Cellular Component	GO:0005634	nucleus	IDA	J:47287
Cellular Component	GO:0005634	nucleus	IDA	J:132583
Cellular Component	GO:0005634	nucleus	IDA	J:95960
Cellular Component	GO:0005634	nucleus	IDA	J:55698
Cellular Component	GO:0005634	nucleus	IDA	J:101729
Cellular Component	GO:0005634	nucleus	IDA	J:101729
Cellular Component	GO:0005634	nucleus	IDA	J:111226
Cellular Component	GO:0005634	nucleus	IDA	J:101729
Cellular Component	GO:0005726	perichromatin fibrils	IDA	J:55698
Cellular Component	GO:0016586	RSC-type complex	NAS	J:35263
Cellular Component	GO:0016514	SWI/SNF complex	NAS	J:35263
Cellular Component	GO:0016514	SWI/SNF complex	ISO	J:155856
Cellular Component	GO:0016514	SWI/SNF complex	ISO	J:164563
Cellular Component	GO:0016514	SWI/SNF complex	IDA	J:283189
Cellular Component	GO:0016514	SWI/SNF complex	TAS	J:66861
Cellular Component	GO:0016514	SWI/SNF complex	IDA	J:103896
Cellular Component	GO:0070603	SWI/SNF superfamily-type complex	IDA	J:156242
Cellular Component	GO:0070603	SWI/SNF superfamily-type complex	IDA	J:212358
Cellular Component	GO:0070603	SWI/SNF superfamily-type complex	IDA	J:212358
Cellular Component	GO:0070603	SWI/SNF superfamily-type complex	IDA	J:212358
Biological Process	GO:0035904	aorta development	IMP	J:222159
Biological Process	GO:0035887	aortic smooth muscle cell differentiation	IMP	J:172496
Biological Process	GO:0001832	blastocyst growth	IMP	J:66861
Biological Process	GO:0001835	blastocyst hatching	IMP	J:66861
Biological Process	GO:0001568	blood vessel development	IMP	J:193698
Biological Process	GO:0000902	cell morphogenesis	IMP	J:103896
Biological Process	GO:0000902	cell morphogenesis	IMP	J:103896
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	ISO	J:155856
Biological Process	GO:0006338	chromatin remodeling	NAS	J:320039
Biological Process	GO:0006338	chromatin remodeling	NAS	J:283189
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0006338	chromatin remodeling	IMP	J:103896
Biological Process	GO:0060976	coronary vasculature development	IMP	J:222159
Biological Process	GO:0060318	definitive erythrocyte differentiation	IMP	J:103896
Biological Process	GO:0010424	DNA methylation on cytosine within a CG sequence	IMP	J:103896
Biological Process	GO:0006346	DNA methylation-dependent heterochromatin formation	IDA	J:104088
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IMP	J:101729
Biological Process	GO:0048562	embryonic organ morphogenesis	IMP	J:103896
Biological Process	GO:0048562	embryonic organ morphogenesis	IMP	J:103896
Biological Process	GO:0048730	epidermis morphogenesis	IMP	J:101729
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:132583
Biological Process	GO:0030900	forebrain development	IMP	J:104327
Biological Process	GO:0010467	gene expression	IDA	J:213053
Biological Process	GO:0007403	glial cell fate determination	IMP	J:104327
Biological Process	GO:0007507	heart development	IMP	J:132583
Biological Process	GO:0060347	heart trabecula formation	IGI	J:132583
Biological Process	GO:0030902	hindbrain development	IMP	J:104327
Biological Process	GO:0043966	histone H3 acetylation	IMP	J:103896
Biological Process	GO:0001701	in utero embryonic development	IMP	J:103896
Biological Process	GO:0001701	in utero embryonic development	IMP	J:193698
Biological Process	GO:0001701	in utero embryonic development	IMP	J:103896
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:101729
Biological Process	GO:0070307	lens fiber cell development	IMP	J:168483
Biological Process	GO:0001889	liver development	IMP	J:103896
Biological Process	GO:0001889	liver development	IMP	J:103896
Biological Process	GO:0060766	negative regulation of androgen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:193698
Biological Process	GO:0045596	negative regulation of cell differentiation	NAS	J:268334
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:193698
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:132583
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:104088
Biological Process	GO:0007399	nervous system development	IMP	J:132090
Biological Process	GO:0022008	neurogenesis	IDA	J:184001
Biological Process	GO:0006334	nucleosome assembly	TAS	J:66861
Biological Process	GO:0006337	nucleosome disassembly	ISO	J:164563
Biological Process	GO:0006337	nucleosome disassembly	ISO	J:155856
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:193698
Biological Process	GO:0061626	pharyngeal arch artery morphogenesis	IMP	J:193698
Biological Process	GO:0043923	positive regulation by host of viral transcription	ISO	J:164563
Biological Process	GO:0045597	positive regulation of cell differentiation	NAS	J:74389
Biological Process	GO:0045597	positive regulation of cell differentiation	NAS	J:156242
Biological Process	GO:0045597	positive regulation of cell differentiation	IMP	J:193698
Biological Process	GO:0008284	positive regulation of cell population proliferation	NAS	J:283189
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:193698
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IDA	J:321533
Biological Process	GO:0043388	positive regulation of DNA binding	IGI	J:172496
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:2000781	positive regulation of double-strand break repair	NAS	J:319964
Biological Process	GO:2000781	positive regulation of double-strand break repair	NAS	J:319983
Biological Process	GO:1902661	positive regulation of glucose mediated signaling pathway	ISO	J:164563
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0045663	positive regulation of myoblast differentiation	NAS	J:319991
Biological Process	GO:0045663	positive regulation of myoblast differentiation	NAS	J:320040
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	NAS	J:147141
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	NAS	J:268334
Biological Process	GO:0045582	positive regulation of T cell differentiation	NAS	J:131676
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:204641
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:193698
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:172496
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:103896
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:103896
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:172496
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:172496
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:172496
Biological Process	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	ISO	J:164563
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	IMP	J:150343
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0060319	primitive erythrocyte differentiation	IMP	J:103896
Biological Process	GO:0030334	regulation of cell migration	IMP	J:193698
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0070316	regulation of G0 to G1 transition	NAS	J:74389
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	NAS	J:320113
Biological Process	GO:0030071	regulation of mitotic metaphase/anaphase transition	NAS	J:319964
Biological Process	GO:0030071	regulation of mitotic metaphase/anaphase transition	NAS	J:198738
Biological Process	GO:2000819	regulation of nucleotide-excision repair	NAS	J:320041
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:68501
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:320308
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:283189
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:320112
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:132101
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:160495
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:172496
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:172496
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	IDA	J:321533
Biological Process	GO:0001570	vasculogenesis	IMP	J:132583
Biological Process	GO:0003281	ventricular septum development	IMP	J:222159