Agt GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Agt
angiotensinogen
MGI:87963

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005179	hormone activity	ISO	J:155856
Molecular Function	GO:0005179	hormone activity	ISO	J:164563
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0017080	sodium channel regulator activity	ISO	J:164563
Molecular Function	GO:0031702	type 1 angiotensin receptor binding	ISO	J:164563
Molecular Function	GO:0031702	type 1 angiotensin receptor binding	IDA	J:51954
Molecular Function	GO:0031702	type 1 angiotensin receptor binding	IDA	J:51954
Molecular Function	GO:0031702	type 1 angiotensin receptor binding	IDA	J:51954
Molecular Function	GO:0031703	type 2 angiotensin receptor binding	ISO	J:164563
Molecular Function	GO:0031703	type 2 angiotensin receptor binding	IPI	J:51954
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:73163
Cellular Component	GO:0005615	extracellular space	IDA	J:21887
Cellular Component	GO:0005615	extracellular space	IDA	J:56635
Biological Process	GO:0007250	activation of NF-kappaB-inducing kinase activity	IDA	J:148250
Biological Process	GO:0007202	activation of phospholipase C activity	ISO	J:155856
Biological Process	GO:0035932	aldosterone secretion	IMP	J:184790
Biological Process	GO:0035932	aldosterone secretion	IMP	J:106325
Biological Process	GO:0038166	angiotensin-activated signaling pathway	ISO	J:164563
Biological Process	GO:0003051	angiotensin-mediated drinking behavior	ISO	J:155856
Biological Process	GO:0001998	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure	IDA	J:56635
Biological Process	GO:0014824	artery smooth muscle contraction	ISO	J:155856
Biological Process	GO:0008306	associative learning	ISO	J:155856
Biological Process	GO:0048143	astrocyte activation	IMP	J:78696
Biological Process	GO:0001568	blood vessel development	IMP	J:30061
Biological Process	GO:0001568	blood vessel development	IMP	J:30061
Biological Process	GO:0001568	blood vessel development	IMP	J:30061
Biological Process	GO:0001568	blood vessel development	IMP	J:46007
Biological Process	GO:0002035	brain renin-angiotensin system	IDA	J:103853
Biological Process	GO:0002035	brain renin-angiotensin system	IDA	J:51954
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IDA	J:82904
Biological Process	GO:0061049	cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:0008283	cell population proliferation	IMP	J:73163
Biological Process	GO:0008283	cell population proliferation	IMP	J:30061
Biological Process	GO:0008283	cell population proliferation	IMP	J:55000
Biological Process	GO:0007166	cell surface receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007160	cell-matrix adhesion	IMP	J:78696
Biological Process	GO:0042756	drinking behavior	IMP	J:78698
Biological Process	GO:0070371	ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0008065	establishment of blood-nerve barrier	IMP	J:78696
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:78696
Biological Process	GO:0048144	fibroblast proliferation	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0042445	hormone metabolic process	IMP	J:83016
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ISO	J:155856
Biological Process	GO:0001822	kidney development	ISO	J:164563
Biological Process	GO:0001822	kidney development	IMP	J:46007
Biological Process	GO:0001822	kidney development	IMP	J:30061
Biological Process	GO:0001822	kidney development	IMP	J:46007
Biological Process	GO:0001822	kidney development	IMP	J:46007
Biological Process	GO:0001822	kidney development	IMP	J:30061
Biological Process	GO:0001822	kidney development	IMP	J:30061
Biological Process	GO:0002034	maintenance of blood vessel diameter homeostasis by renin-angiotensin	ISO	J:164563
Biological Process	GO:0000165	MAPK cascade	IMP	J:41022
Biological Process	GO:0000165	MAPK cascade	IMP	J:41022
Biological Process	GO:0016525	negative regulation of angiogenesis	ISO	J:155856
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:73163
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:78697
Biological Process	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway	ISO	J:164563
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	IMP	J:30061
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	IMP	J:55000
Biological Process	GO:0034104	negative regulation of tissue remodeling	ISO	J:155856
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	IMP	J:30061
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:78697
Biological Process	GO:0035106	operant conditioning	ISO	J:155856
Biological Process	GO:0035265	organ growth	IDA	J:105371
Biological Process	GO:0001543	ovarian follicle rupture	IMP	J:69609
Biological Process	GO:0030432	peristalsis	IMP	J:51021
Biological Process	GO:0010536	positive regulation of activation of Janus kinase activity	ISO	J:164563
Biological Process	GO:0045777	positive regulation of blood pressure	ISO	J:155856
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	ISO	J:164563
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	ISO	J:155856
Biological Process	GO:0043085	positive regulation of catalytic activity	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:1905920	positive regulation of CoA-transferase activity	ISO	J:164563
Biological Process	GO:0001819	positive regulation of cytokine production	IMP	J:156435
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010595	positive regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0003331	positive regulation of extracellular matrix constituent secretion	ISO	J:155856
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	IMP	J:73163
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:155856
Biological Process	GO:1903598	positive regulation of gap junction assembly	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:148250
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:148250
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	ISO	J:155856
Biological Process	GO:1905589	positive regulation of L-arginine import across plasma membrane	ISO	J:155856
Biological Process	GO:1905010	positive regulation of L-lysine import across plasma membrane	ISO	J:155856
Biological Process	GO:0010744	positive regulation of macrophage derived foam cell differentiation	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:41022
Biological Process	GO:1902632	positive regulation of membrane hyperpolarization	ISO	J:164563
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:83016
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	ISO	J:155856
Biological Process	GO:0046622	positive regulation of organ growth	IDA	J:105371
Biological Process	GO:0046622	positive regulation of organ growth	IMP	J:83016
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	IDA	J:204720
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:1900020	positive regulation of protein kinase C activity	IDA	J:204720
Biological Process	GO:1900020	positive regulation of protein kinase C activity	IDA	J:204720
Biological Process	GO:0051247	positive regulation of protein metabolic process	ISO	J:164563
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	ISO	J:164563
Biological Process	GO:0035815	positive regulation of renal sodium excretion	ISO	J:155856
Biological Process	GO:0032930	positive regulation of superoxide anion generation	ISO	J:155856
Biological Process	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	ISO	J:155856
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0006606	protein import into nucleus	ISO	J:155856
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0042981	regulation of apoptotic process	IBA	J:265628
Biological Process	GO:0042981	regulation of apoptotic process	IDA	J:148250
Biological Process	GO:0008217	regulation of blood pressure	ISO	J:164563
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:106325
Biological Process	GO:0051924	regulation of calcium ion transport	ISO	J:155856
Biological Process	GO:1903779	regulation of cardiac conduction	ISO	J:164563
Biological Process	GO:1901201	regulation of extracellular matrix assembly	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	IDA	J:121666
Biological Process	GO:0002027	regulation of heart rate	ISO	J:155856
Biological Process	GO:0050727	regulation of inflammatory response	IGI	J:148250
Biological Process	GO:0050727	regulation of inflammatory response	IDA	J:148250
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	ISO	J:155856
Biological Process	GO:0014061	regulation of norepinephrine secretion	ISO	J:155856
Biological Process	GO:0002019	regulation of renal output by angiotensin	IMP	J:46506
Biological Process	GO:0002019	regulation of renal output by angiotensin	IMP	J:73163
Biological Process	GO:0002019	regulation of renal output by angiotensin	IMP	J:78698
Biological Process	GO:0035813	regulation of renal sodium excretion	ISO	J:155856
Biological Process	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	IMP	J:21887
Biological Process	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	IMP	J:78698
Biological Process	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	IMP	J:46007
Biological Process	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	IMP	J:102953
Biological Process	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	IMP	J:46506
Biological Process	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	IMP	J:53591
Biological Process	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	IMP	J:73163
Biological Process	GO:0051969	regulation of transmission of nerve impulse	ISO	J:155856
Biological Process	GO:0001999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure	IMP	J:73163
Biological Process	GO:0003014	renal system process	ISO	J:164563
Biological Process	GO:0002018	renin-angiotensin regulation of aldosterone production	ISO	J:155856
Biological Process	GO:0002018	renin-angiotensin regulation of aldosterone production	IMP	J:78698
Biological Process	GO:0002018	renin-angiotensin regulation of aldosterone production	IMP	J:53591
Biological Process	GO:0009409	response to cold	IMP	J:102953
Biological Process	GO:0014873	response to muscle activity involved in regulation of muscle adaptation	ISO	J:155856
Biological Process	GO:0009651	response to salt stress	IMP	J:106325
Biological Process	GO:0051145	smooth muscle cell differentiation	IMP	J:51021
Biological Process	GO:0051145	smooth muscle cell differentiation	IDA	J:51021
Biological Process	GO:0048659	smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0048659	smooth muscle cell proliferation	IMP	J:55000
Biological Process	GO:0048659	smooth muscle cell proliferation	IMP	J:30061
Biological Process	GO:0048659	smooth muscle cell proliferation	IMP	J:51021
Biological Process	GO:0048659	smooth muscle cell proliferation	IDA	J:51021
Biological Process	GO:0051403	stress-activated MAPK cascade	ISO	J:155856
Biological Process	GO:0070471	uterine smooth muscle contraction	ISO	J:155856
Biological Process	GO:1990874	vascular associated smooth muscle cell proliferation	IMP	J:30061
Biological Process	GO:0042310	vasoconstriction	ISO	J:155856
Biological Process	GO:0042311	vasodilation	ISO	J:155856
Biological Process	GO:0030103	vasopressin secretion	IMP	J:106325

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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