GO Annotations Graph

• Symbol: Ano2
• Name: anoctamin 2
• ID: MGI:2387214

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005254	chloride channel activity	TAS	Reactome:R-MMU-9714186
Molecular Function	GO:0005254	chloride channel activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:196141
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	ISO	J:155856
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IDA	J:155179
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	ISO	J:164563
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IDA	J:155364
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IDA	J:190271
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IDA	J:149521
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IMP	J:173937
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IDA	J:165954
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IDA	J:198369
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IDA	J:198369
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IMP	J:173937
Molecular Function	GO:0005515	protein binding	IPI	J:149521
Molecular Function	GO:0005515	protein binding	IPI	J:196141
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Cellular Component	GO:0034707	chloride channel complex	IEA	J:60000
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:149521
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:149521
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IDA	J:173937
Cellular Component	GO:0043005	neuron projection	IDA	J:173937
Cellular Component	GO:0097730	non-motile cilium	IDA	J:173937
Cellular Component	GO:0097730	non-motile cilium	IDA	J:173937
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:149521
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9714186
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:165954
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:149521
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:149521
Biological Process	GO:1902476	chloride transmembrane transport	IBA	J:265628
Biological Process	GO:0006821	chloride transport	IMP	J:173937
Biological Process	GO:0006821	chloride transport	IMP	J:173937
Biological Process	GO:0006821	chloride transport	IDA	J:198369
Biological Process	GO:0006821	chloride transport	IDA	J:198369
Biological Process	GO:0006821	chloride transport	IDA	J:165954
Biological Process	GO:0051649	establishment of localization in cell	IDA	J:198369
Biological Process	GO:0051649	establishment of localization in cell	IDA	J:198369
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:173937
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:173937
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000