Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables identical protein binding activity and intracellularly calcium-gated chloride channel activity. Acts upstream of or within chloride transport and establishment of localization in cell. Located in neuron projection; non-motile cilium; and plasma membrane. Is active in glutamatergic synapse and presynaptic membrane. Is expressed in dorsal root ganglion; epidermis; medulla oblongata basal plate mantle layer; olfactory epithelium; and spinal cord mantle layer. Orthologous to human ANO2 (anoctamin 2).