GO Annotations Graph

• Symbol: Cblb
• Name: Casitas B-lineage lymphoma b
• ID: MGI:2146430

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0001784	phosphotyrosine residue binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:239186
Molecular Function	GO:0005515	protein binding	IPI	J:162535
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:84101
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0030971	receptor tyrosine kinase binding	IBA	J:265628
Molecular Function	GO:0017124	SH3 domain binding	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	IMP	J:89097
Biological Process	GO:0007166	cell surface receptor signaling pathway	IEA	J:72247
Biological Process	GO:0006955	immune response	IMP	J:79550
Biological Process	GO:0035556	intracellular signal transduction	IMP	J:79550
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	IMP	J:89097
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	IBA	J:265628
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	IMP	J:89761
Biological Process	GO:0018193	peptidyl-amino acid modification	IDA	J:84101
Biological Process	GO:0045732	positive regulation of protein catabolic process	IMP	J:89097
Biological Process	GO:0031398	positive regulation of protein ubiquitination	IDA	J:84101
Biological Process	GO:0002669	positive regulation of T cell anergy	IMP	J:89097
Biological Process	GO:0030163	protein catabolic process	IMP	J:89097
Biological Process	GO:0030155	regulation of cell adhesion	IMP	J:84101
Biological Process	GO:0043087	regulation of GTPase activity	IMP	J:84101
Biological Process	GO:2000583	regulation of platelet-derived growth factor receptor-alpha signaling pathway	IMP	J:281256
Biological Process	GO:0043393	regulation of protein binding	IMP	J:84101
Biological Process	GO:0023051	regulation of signaling	IEA	J:72247
Biological Process	GO:0050856	regulation of T cell receptor signaling pathway	ISO	J:230444
Biological Process	GO:0007165	signal transduction	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0042110	T cell activation	IMP	J:79550
Biological Process	GO:0002870	T cell anergy	IMP	J:89097
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:84101