GO Annotations Graph

• Symbol: Ncoa6
• Name: nuclear receptor coactivator 6
• ID: MGI:1929915

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:80609
Molecular Function	GO:0140463	chromatin-protein adaptor activity	IMP	J:116064
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:1990226	histone methyltransferase binding	IPI	J:116064
Molecular Function	GO:1990226	histone methyltransferase binding	IPI	J:116064
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:155856
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	ISO	J:155856
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:155856
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:164563
Molecular Function	GO:0030374	nuclear receptor coactivator activity	IBA	J:265628
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	ISO	J:155856
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	ISO	J:155856
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	ISO	J:155856
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	ISO	J:164563
Molecular Function	GO:0042809	nuclear vitamin D receptor binding	ISO	J:155856
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	ISO	J:155856
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:62059
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0035097	histone methyltransferase complex	IBA	J:265628
Cellular Component	GO:0035097	histone methyltransferase complex	ISO	J:123598
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0044666	MLL3/4 complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617960
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617990
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619411
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619424
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619430
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619434
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619436
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619437
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619440
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619441
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621004
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621012
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5693628
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810150
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810169
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810170
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:123598
Cellular Component	GO:0005634	nucleus	IDA	J:62059
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:60556
Biological Process	GO:0007420	brain development	IMP	J:81818
Biological Process	GO:0006974	DNA damage response	ISO	J:123598
Biological Process	GO:0006352	DNA-templated transcription initiation	ISO	J:164563
Biological Process	GO:0007507	heart development	IMP	J:81818
Biological Process	GO:0007507	heart development	IMP	J:80175
Biological Process	GO:0060716	labyrinthine layer blood vessel development	IMP	J:81818
Biological Process	GO:0060716	labyrinthine layer blood vessel development	IMP	J:80175
Biological Process	GO:0030099	myeloid cell differentiation	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:81818
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:60556
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0002793	positive regulation of peptide secretion	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0010468	regulation of gene expression	IMP	J:116064