Automated description from the Alliance of Genome Resources (Release 5.4.0)
Enables several functions, including chromatin-protein adaptor activity; histone methyltransferase binding activity; and transcription coactivator activity. Acts upstream of or within brain development; circulatory system development; and positive regulation of DNA-templated transcription. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in breast cancer; colon cancer; and lung cancer. Orthologous to human NCOA6 (nuclear receptor coactivator 6).