GO Annotations Graph

• Symbol: Kdm5b
• Name: lysine demethylase 5B
• ID: MGI:1922855

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051213	dioxygenase activity	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0032452	histone demethylase activity	IBA	J:265628
Molecular Function	GO:0032453	histone H3K4 demethylase activity	ISO	J:164563
Molecular Function	GO:0032453	histone H3K4 demethylase activity	IDA	J:122689
Molecular Function	GO:0034647	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	ISO	J:164563
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:171270
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0060444	branching involved in mammary gland duct morphogenesis	IMP	J:218960
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	IBA	J:265628
Biological Process	GO:0060763	mammary duct terminal end bud growth	IMP	J:218960
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:176119
Biological Process	GO:0010628	positive regulation of gene expression	IGI	J:218960
Biological Process	GO:0033601	positive regulation of mammary gland epithelial cell proliferation	IMP	J:218960
Biological Process	GO:0009791	post-embryonic development	IMP	J:218960
Biological Process	GO:0042752	regulation of circadian rhythm	NAS	J:176119
Biological Process	GO:2000864	regulation of estradiol secretion	IMP	J:218960
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0007338	single fertilization	IMP	J:218960
Biological Process	GO:0061038	uterus morphogenesis	IMP	J:218960