GO Annotations Graph

• Symbol: Mad2l2
• Name: MAD2 mitotic arrest deficient-like 2
• ID: MGI:1919140

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008432	JUN kinase binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Cellular Component	GO:0005680	anaphase-promoting complex	ISO	J:164563
Cellular Component	GO:0000785	chromatin	NAS	J:261998
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0035861	site of double-strand break	NAS	J:261998
Cellular Component	GO:0005819	spindle	ISO	J:164563
Cellular Component	GO:0016035	zeta DNA polymerase complex	ISO	J:164563
Cellular Component	GO:0016035	zeta DNA polymerase complex	IBA	J:265628
Biological Process	GO:0007015	actin filament organization	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0042772	DNA damage response, signal transduction resulting in transcription	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0006302	double-strand break repair	ISO	J:164563
Biological Process	GO:0042276	error-prone translesion synthesis	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	ISO	J:164563
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0042177	negative regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0010944	negative regulation of transcription by competitive promoter binding	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:2000678	negative regulation of transcription regulatory region DNA binding	ISO	J:164563
Biological Process	GO:1904667	negative regulation of ubiquitin protein ligase activity	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	NAS	J:261998
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	ISO	J:155856
Biological Process	GO:1901203	positive regulation of extracellular matrix assembly	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0045830	positive regulation of isotype switching	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0001558	regulation of cell growth	ISO	J:164563
Biological Process	GO:0002208	somatic diversification of immunoglobulins involved in immune response	NAS	J:261998
Biological Process	GO:0043247	telomere maintenance in response to DNA damage	NAS	J:261998