GO Annotations Graph

• Symbol: Tnfsf13
• Name: tumor necrosis factor (ligand) superfamily, member 13
• ID: MGI:1916833

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IEA	J:60000
Molecular Function	GO:0048018	receptor ligand activity	IBA	J:265628
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:87680
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:72247
Biological Process	GO:0002467	germinal center formation	IMP	J:88910
Biological Process	GO:0006955	immune response	IEA	J:72247
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0016064	immunoglobulin mediated immune response	IMP	J:88910
Biological Process	GO:0002426	immunoglobulin production in mucosal tissue	IMP	J:88910
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:71877
Biological Process	GO:0002636	positive regulation of germinal center formation	IMP	J:88910
Biological Process	GO:0048298	positive regulation of isotype switching to IgA isotypes	IBA	J:265628
Biological Process	GO:0048298	positive regulation of isotype switching to IgA isotypes	IMP	J:88910
Biological Process	GO:0048298	positive regulation of isotype switching to IgA isotypes	ISO	J:88910
Biological Process	GO:0050776	regulation of immune response	IMP	J:88910