GO Annotations Graph

• Symbol: Nr2c1
• Name: nuclear receptor subfamily 2, group C, member 1
• ID: MGI:1352465

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:38523
Molecular Function	GO:0003677	DNA binding	IDA	J:50521
Molecular Function	GO:0003677	DNA binding	IDA	J:113832
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:113832
Molecular Function	GO:0042826	histone deacetylase binding	IPI	J:114039
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:175152
Molecular Function	GO:0005515	protein binding	IPI	J:245382
Molecular Function	GO:0005515	protein binding	IPI	J:175152
Molecular Function	GO:0005515	protein binding	IPI	J:50521
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:113832
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:113832
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IEA	J:72247
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4717491
Cellular Component	GO:0005634	nucleus	IDA	J:122686
Cellular Component	GO:0016605	PML body	IDA	J:175152
Biological Process	GO:0048856	anatomical structure development	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:113832
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:34527
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:50521
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:38523
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:50521
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:113832
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:34527
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:38523
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0048386	positive regulation of retinoic acid receptor signaling pathway	IDA	J:175360
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247