GO Annotations Graph

• Symbol: Mta2
• Name: metastasis-associated gene family, member 2
• ID: MGI:1346340

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0004407	histone deacetylase activity	IDA	J:56739
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:155856
Molecular Function	GO:0042826	histone deacetylase binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:184123
Molecular Function	GO:0005515	protein binding	IPI	J:160317
Molecular Function	GO:0005515	protein binding	IPI	J:222151
Molecular Function	GO:0005515	protein binding	IPI	J:148391
Molecular Function	GO:0005515	protein binding	IPI	J:166393
Molecular Function	GO:0005515	protein binding	IPI	J:206161
Molecular Function	GO:0005515	protein binding	IPI	J:182157
Molecular Function	GO:0005515	protein binding	IPI	J:319940
Molecular Function	GO:0005515	protein binding	IPI	J:272747
Molecular Function	GO:0005515	protein binding	IPI	J:170044
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:156979
Molecular Function	GO:0005515	protein binding	IPI	J:87046
Molecular Function	GO:0005515	protein binding	IPI	J:106974
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:87046
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:87046
Molecular Function	GO:0005515	protein binding	IPI	J:106974
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:106974
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IEA	J:72247
Molecular Function	GO:0003713	transcription coactivator activity	IBA	J:265628
Molecular Function	GO:0003712	transcription coregulator activity	IDA	J:166393
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0000118	histone deacetylase complex	IDA	J:56739
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-573373
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-573385
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:106974
Cellular Component	GO:0005634	nucleus	IDA	J:168362
Cellular Component	GO:0005634	nucleus	IDA	J:168362
Cellular Component	GO:0005634	nucleus	IDA	J:72922
Cellular Component	GO:0005634	nucleus	IDA	J:168362
Cellular Component	GO:0005634	nucleus	IDA	J:168362
Cellular Component	GO:0016581	NuRD complex	ISO	J:164563
Cellular Component	GO:0016581	NuRD complex	NAS	J:319987
Cellular Component	GO:0016581	NuRD complex	IBA	J:265628
Cellular Component	GO:0016581	NuRD complex	IPI	J:106974
Cellular Component	GO:0016581	NuRD complex	IDA	J:87046
Cellular Component	GO:0016581	NuRD complex	IPI	J:106974
Cellular Component	GO:0016581	NuRD complex	IPI	J:106974
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0006338	chromatin remodeling	TAS	J:87046
Biological Process	GO:0051276	chromosome organization	TAS	J:56739
Biological Process	GO:0006306	DNA methylation	IMP	J:168362
Biological Process	GO:0016575	histone deacetylation	ISO	J:164563
Biological Process	GO:0016575	histone deacetylation	IBA	J:265628
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NAS	J:319679
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:166393
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:72922
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NAS	J:156393
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:72922
Biological Process	GO:0042659	regulation of cell fate specification	NAS	J:319679
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010762	regulation of fibroblast migration	ISO	J:155856
Biological Process	GO:2000736	regulation of stem cell differentiation	NAS	J:319679