GO Annotations Graph

• Symbol: Bard1
• Name: BRCA1 associated RING domain 1
• ID: MGI:1328361

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	ISO	J:79872
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	IBA	J:265628
Cellular Component	GO:0070531	BRCA1-A complex	ISO	J:164563
Cellular Component	GO:0070531	BRCA1-A complex	NAS	J:320081
Cellular Component	GO:0070531	BRCA1-A complex	IBA	J:265628
Cellular Component	GO:0070532	BRCA1-B complex	ISO	J:164563
Cellular Component	GO:0031436	BRCA1-BARD1 complex	ISO	J:164563
Cellular Component	GO:0031436	BRCA1-BARD1 complex	IBA	J:265628
Cellular Component	GO:0070533	BRCA1-C complex	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0000152	nuclear ubiquitin ligase complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	NAS	J:320080
Cellular Component	GO:0005634	nucleus	NAS	J:320081
Cellular Component	GO:0005634	nucleus	NAS	J:319979
Cellular Component	GO:0005634	nucleus	IDA	J:71817
Biological Process	GO:0071479	cellular response to ionizing radiation	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	NAS	J:319986
Biological Process	GO:0006281	DNA repair	NAS	J:320080
Biological Process	GO:0110025	DNA strand resection involved in replication fork processing	NAS	J:320083
Biological Process	GO:0070537	histone H2A K63-linked deubiquitination	NAS	J:320081
Biological Process	GO:0035518	histone H2A monoubiquitination	NAS	J:320082
Biological Process	GO:0035825	homologous recombination	NAS	J:319683
Biological Process	GO:0035825	homologous recombination	NAS	J:320080
Biological Process	GO:0044818	mitotic G2/M transition checkpoint	NAS	J:320080
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0046826	negative regulation of protein export from nucleus	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0045787	positive regulation of cell cycle	NAS	J:319994
Biological Process	GO:0051865	protein autoubiquitination	NAS	J:320082
Biological Process	GO:0085020	protein K6-linked ubiquitination	ISO	J:164563
Biological Process	GO:0085020	protein K6-linked ubiquitination	IBA	J:265628
Biological Process	GO:0000209	protein polyubiquitination	ISO	J:164563
Biological Process	GO:2000001	regulation of DNA damage checkpoint	NAS	J:320084
Biological Process	GO:0006282	regulation of DNA repair	NAS	J:320081
Biological Process	GO:0042325	regulation of phosphorylation	ISO	J:164563