GO Annotations Graph

• Symbol: Ezh1
• Name: enhancer of zeste 1 polycomb repressive complex 2 subunit
• ID: MGI:1097695

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0042393	histone binding	IDA	J:142192
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	IDA	J:148710
Molecular Function	GO:0140951	histone H3K27 trimethyltransferase activity	IEA	J:72245
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:157724
Molecular Function	GO:0005515	protein binding	IPI	J:47703
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:142192
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	IGI	J:41121
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:157724
Cellular Component	GO:0035098	ESC/E(Z) complex	ISO	J:164563
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:142192
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:183475
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:157068
Cellular Component	GO:0035098	ESC/E(Z) complex	IBA	J:265628
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:281161
Cellular Component	GO:0000792	heterochromatin	IDA	J:142192
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:47703
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	IDA	J:142192
Biological Process	GO:0140718	facultative heterochromatin formation	IDA	J:157724
Biological Process	GO:0036333	hepatocyte homeostasis	IGI	J:220905
Biological Process	GO:0031507	heterochromatin formation	IDA	J:142192
Biological Process	GO:0031507	heterochromatin formation	IBA	J:265628
Biological Process	GO:0070734	histone H3-K27 methylation	IEA	J:72247
Biological Process	GO:0098532	histone H3-K27 trimethylation	IBA	J:265628
Biological Process	GO:0097421	liver regeneration	IGI	J:220905
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:142192
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:148710
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:1904772	response to tetrachloromethane	IGI	J:220905
Biological Process	GO:0031509	subtelomeric heterochromatin formation	IGI	J:41121