Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables histone H3K27 methyltransferase activity and transcription corepressor activity. Contributes to histone binding activity. Involved in facultative heterochromatin formation; negative regulation of transcription by RNA polymerase II; and subtelomeric heterochromatin formation. Acts upstream of or within hepatocyte homeostasis; liver regeneration; and response to tetrachloromethane. Located in chromosome, telomeric region and nucleus. Part of ESC/E(Z) complex and heterochromatin. Is expressed in several structures, including genitourinary system; immune system; retina nuclear layer; tail; and trunk. Orthologous to human EZH1 (enhancer of zeste 1 polycomb repressive complex 2 subunit).