GO Annotations Graph

• Symbol: Pias2
• Name: protein inhibitor of activated STAT 2
• ID: MGI:1096566

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:42027
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0050681	nuclear androgen receptor binding	ISO	J:155856
Molecular Function	GO:0050681	nuclear androgen receptor binding	ISO	J:52591
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:155856
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:112691
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:217988
Molecular Function	GO:0061665	SUMO ligase activity	ISO	J:164563
Molecular Function	GO:0061665	SUMO ligase activity	ISO	J:164563
Molecular Function	GO:0061665	SUMO ligase activity	IBA	J:265628
Molecular Function	GO:0019789	SUMO transferase activity	EXP	J:262338
Molecular Function	GO:0019789	SUMO transferase activity	ISO	J:164563
Molecular Function	GO:0019789	SUMO transferase activity	EXP	J:262359
Molecular Function	GO:0019789	SUMO transferase activity	EXP	J:140756
Molecular Function	GO:0019789	SUMO transferase activity	EXP	J:262418
Molecular Function	GO:0019789	SUMO transferase activity	IDA	J:97581
Molecular Function	GO:0003712	transcription coregulator activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:172990
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4717507
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:112691
Cellular Component	GO:0005634	nucleus	ISO	J:52591
Cellular Component	GO:0016605	PML body	ISO	J:164563
Biological Process	GO:0030521	androgen receptor signaling pathway	ISO	J:155856
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:42027
Biological Process	GO:0060766	negative regulation of androgen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0016925	protein sumoylation	ISO	J:164563
Biological Process	GO:0016925	protein sumoylation	ISO	J:164563
Biological Process	GO:0016925	protein sumoylation	IBA	J:265628
Biological Process	GO:0016925	protein sumoylation	IDA	J:97581
Biological Process	GO:0060765	regulation of androgen receptor signaling pathway	ISO	J:52591
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:42027