GO Annotations Graph

• Symbol: Ube2i
• Name: ubiquitin-conjugating enzyme E2I
• ID: MGI:107365

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0043425	bHLH transcription factor binding	ISO	J:155856
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0043398	HLH domain binding	IPI	J:44342
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:200491
Molecular Function	GO:0005515	protein binding	IPI	J:245382
Molecular Function	GO:0005515	protein binding	IPI	J:235235
Molecular Function	GO:0005515	protein binding	IPI	J:97581
Molecular Function	GO:0005515	protein binding	IPI	J:41993
Molecular Function	GO:0005515	protein binding	IPI	J:82289
Molecular Function	GO:0005515	protein binding	IPI	J:65403
Molecular Function	GO:0071535	RING-like zinc finger domain binding	ISO	J:164563
Molecular Function	GO:0044388	small protein activating enzyme binding	ISO	J:164563
Molecular Function	GO:0061656	SUMO conjugating enzyme activity	ISO	J:164563
Molecular Function	GO:0061656	SUMO conjugating enzyme activity	IBA	J:265628
Molecular Function	GO:0019789	SUMO transferase activity	ISO	J:155856
Molecular Function	GO:0019789	SUMO transferase activity	ISO	J:164563
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Molecular Function	GO:0008134	transcription factor binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-4655356
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0001650	fibrillar center	ISO	J:155856
Cellular Component	GO:0016604	nuclear body	IDA	J:142156
Cellular Component	GO:0016604	nuclear body	ISO	J:155856
Cellular Component	GO:0005635	nuclear envelope	ISO	J:155856
Cellular Component	GO:0005643	nuclear pore	NAS	J:319956
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-3903005
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-3927808
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-3927825
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4616026
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4655356
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4655387
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4717491
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4717507
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4755534
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5228515
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912506
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0016605	PML body	ISO	J:164563
Cellular Component	GO:0106068	SUMO ligase complex	ISO	J:164563
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:1990234	transferase complex	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0007059	chromosome segregation	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:101497
Biological Process	GO:0051168	nuclear export	ISO	J:164563
Biological Process	GO:0051168	nuclear export	EXP	J:319956
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IDA	J:41993
Biological Process	GO:1903755	positive regulation of SUMO transferase activity	ISO	J:164563
Biological Process	GO:0036211	protein modification process	TAS	J:118820
Biological Process	GO:0016925	protein sumoylation	ISO	J:164563
Biological Process	GO:0016925	protein sumoylation	IBA	J:265628