GO Annotations Graph

• Symbol: Zic1
• Name: zinc finger protein of the cerebellum 1
• ID: MGI:106683

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:169807
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:169807
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:93136
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:114033
Molecular Function	GO:0005515	protein binding	IPI	J:169910
Molecular Function	GO:0005515	protein binding	IPI	J:114033
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:169807
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:136993
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:169910
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:114033
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:169910
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0007628	adult walking behavior	IMP	J:73794
Biological Process	GO:0007420	brain development	IDA	J:31270
Biological Process	GO:0007420	brain development	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IGI	J:121744
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0007417	central nervous system development	IBA	J:265628
Biological Process	GO:0007417	central nervous system development	IGI	J:73494
Biological Process	GO:0007417	central nervous system development	IMP	J:73794
Biological Process	GO:0030900	forebrain development	IGI	J:121744
Biological Process	GO:0010467	gene expression	IDA	J:170532
Biological Process	GO:0021766	hippocampus development	IGI	J:121744
Biological Process	GO:0098727	maintenance of cell number	IGI	J:121744
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0021772	olfactory bulb development	IGI	J:121744
Biological Process	GO:0007389	pattern specification process	IDA	J:38554
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:93136
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:114033
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:169807
Biological Process	GO:0042307	positive regulation of protein import into nucleus	IDA	J:114033
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:169807
Biological Process	GO:0008589	regulation of smoothened signaling pathway	IPI	J:114033
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0001501	skeletal system development	NAS	J:114033
Biological Process	GO:0021510	spinal cord development	IMP	J:76132