GO Annotations Graph

• Symbol: Tle4
• Name: transducin-like enhancer of split 4
• ID: MGI:104633

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:101190
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:169294
Molecular Function	GO:0005515	protein binding	IPI	J:266471
Molecular Function	GO:0005515	protein binding	IPI	J:96431
Molecular Function	GO:0005515	protein binding	IPI	J:89367
Molecular Function	GO:0005515	protein binding	IPI	J:101190
Molecular Function	GO:0005515	protein binding	IPI	J:96431
Molecular Function	GO:0005515	protein binding	IPI	J:77680
Molecular Function	GO:0005515	protein binding	IPI	J:89367
Molecular Function	GO:0005515	protein binding	IPI	J:101190
Molecular Function	GO:0005515	protein binding	IPI	J:77680
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:169294
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:89367
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:77680
Molecular Function	GO:0003714	transcription corepressor activity	IGI	J:101190
Molecular Function	GO:0003714	transcription corepressor activity	IGI	J:101190
Molecular Function	GO:0003714	transcription corepressor activity	IGI	J:96431
Molecular Function	GO:0003714	transcription corepressor activity	IGI	J:96431
Molecular Function	GO:0003714	transcription corepressor activity	IGI	J:96431
Cellular Component	GO:1990907	beta-catenin-TCF complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:266471
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IC	J:89367
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:169294
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:77680
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:101190
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:89367