About   Help   FAQ
Rabggtb Gene Detail
Summary
  • Symbol
    Rabggtb
  • Name
    Rab geranylgeranyl transferase, b subunit
  • Feature Type
    protein coding gene
  • IDs
    MGI:99537
    NCBI Gene: 19352
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:153612926-153618603 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 78.76 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    254 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99537
 protein coding gene Chr3:153612924-153618646 (-)
129S1/SvImJ ENSMUSG00200002455
 protein coding gene Chr3:150582276-150587986 (-)
A/J ENSMUSG00195003190
 protein coding gene Chr3:150699467-150705189 (-)
AKR/J ENSMUSG00220000197
 protein coding gene Chr3:149104000-149109710 (-)
BALB/cJ ENSMUSG00180025928
 protein coding gene Chr3:150551436-150557158 (-)
C3H/HeJ ENSMUSG00175018168
 protein coding gene Chr3:150168003-150173725 (-)
C57BL/6NJ ENSMUSG00215012455
 protein coding gene Chr3:150811408-150817130 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025751
 protein coding gene Chr3:146899532-146905183 (-)
CAST/EiJ ENSTCUG00005001041
 protein coding gene Chr3:151223930-151229647 (-)
CBA/J ENSMUSG00210003726
 protein coding gene Chr3:150807958-150813668 (-)
DBA/2J ENSMUSG00185024166
 protein coding gene Chr3:151437558-151443280 (-)
FVB/NJ ENSMUSG00205009170
 protein coding gene Chr3:149737275-149742985 (-)
JF1/MsJ ENSUMUG00000032789
 protein coding gene Chr3:150202577-150208271 (-)
LP/J ENSMUSG00230008979
 protein coding gene Chr3:153331338-153337048 (-)
NOD/ShiLtJ ENSMUSG00190004418
 protein coding gene Chr3:151791659-151797381 (-)
NZO/HlLtJ ENSMUSG00225004797
 protein coding gene Chr3:155832226-155837948 (-)
PWK/PhJ ENSLUMG00010001801
 protein coding gene Chr3:150128829-150134514 (-)
SPRET/EiJ ENSMSPG00010008028
 protein coding gene Chr3:151452964-151458685 (-)
WSB/EiJ ENSIUOG00005015038
 protein coding gene Chr3:150902347-150908069 (-)



Homology
more
  • Human Ortholog
    RABGGTB, Rab geranylgeranyltransferase subunit beta
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RABGGTB, Rab geranylgeranyltransferase subunit beta
  • Synonyms
    GGTB
  • Links
    NCBI Gene ID: 5876
    UniProt: P53611

  • Chr Location
    1p31.1; chr1:75786188-75795090 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    648
  • Tissues
    34
  • cDNA Data
    126
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19352 NCBI Gene Model | MGI Sequence Detail 5678 C57BL/6J ±  kb
transcript NR_028096 RefSeq | MGI Sequence Detail 1574 ZRU/MplStud  
polypeptide P53612 UniProt | EBI | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 133
    cDNA 128
    Primer pair 1
    Other 4

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-16315
References
more
  • Summaries
    All 47
    Developmental Gene Expression 2
    Gene Ontology 13
    Phenotypes 10
  • Earliest
    J:354368 Andres DA, et al., cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein. Cell. 1993 Jun 18;73(6):1091-9
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory