Zfa-ps Pseudogene Detail

Summary

• Symbol
  Zfa-ps
• Name
  zinc finger protein, autosomal, pseudogene
• Synonyms
  Zfa

• Feature Type
  pseudogene
• IDs
  MGI:99153
  NCBI Gene: 22639
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr10:52418416-52421835 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 10, 26.71 cM, cytoband B3-B4
• Mapping Data
  15 experiments

Strain
Comparison

• SNPs within 2kb
  63 from dbSNP Build 142
• Strain Annotations
  8
• RFLP
  8

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_99153	pseudogene	Chr10:52418416-52421835 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0039769	pseudogene	ChrX:90464667-90485840 (-)
A/J	no annotation
AKR/J	MGP_AKRJ_G0039576	pseudogene	Chr10:51153325-51160600 (-)
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0036924	pseudogene	ChrX:88718772-88738594 (-)
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	MGP_FVBNJ_G0039404	pseudogene	Chr10:48935184-48943023 (-)
LP/J	MGP_LPJ_G0035805	pseudogene	ChrX:91252000-91272312 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0040282	pseudogene	Chr10:51066447-51070409 (-)
PWK/PhJ	MGP_PWKPhJ_G0038194	pseudogene	ChrX:73285336-73305693 (-)
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  ZFX, zinc finger protein X-linked

• Vertebrate Orthologs
  4

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  ZFX, zinc finger protein X-linked
  
• Synonyms
  ZNF926
• Links
  HGNC:12869

  NCBI Gene ID: 7543

  neXtProt AC: NX_P17010

  UniProt: P17010

  
  
• Chr Location
  Xp22.11; chrX:24148994-24216255 (+)  GRCh38.p7

---

• Human Ortholog
  ZFY, zinc finger protein Y-linked
  
• Synonyms
  ZNF911
• Links
  HGNC:12870

  NCBI Gene ID: 7544

  neXtProt AC: NX_P08048

  UniProt: P08048

  
  
• Chr Location
  Yp11.2; chrY:2934402-2982508 (+)  GRCh38.p7

---

• Alliance of Genome Resources
  Zfa-ps stringent orthology
  2 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: ZFX, ZFY
• Gene Tree
  Zfa-ps
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 3 genetic backgrounds
  8 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Radiation induced
  1
• Targeted
  1
• Genomic Mutations
  2 involving Zfa-ps
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  22 strains or lines available

Male homozygous null were fertile and showed no spermatogenic or testicular defects.

Expression

• Assay Results
  772
• Tissues
  19
• cDNA Data
  6
• Literature Summary
  2

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Zfa-ps interacts with 148 markers (Mir7-1, Mir9-1, Mir9-2, ...) View All

Sequences &
Gene Models

• All Sequences
  16
• RefSeq
  1
• UniProt
  1
• CCDS
  CCDS23842.1

• Ensembl
  ENSMUSG00000049576 (Evidence)
• NCBI Gene
  22639

Representative Sequences			Length	Strain/Species
genomic	22639	NCBI Gene Model | MGI Sequence Detail	3420	C57BL/6J
transcript	NR_037920	RefSeq | MGI Sequence Detail	3420	C57BL/6
polypeptide	P23607	UniProt | EBI | MGI Sequence Detail	742	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000018244 zinc finger autosomal protein
  (term hierarchy)

Molecular
Reagents

• All nucleic 17

  Genomic 3

  cDNA 8

  Primer pair 2

  Other 4

  
  

  Microarray probesets 1

Other
Accession IDs

MGD-MRK-15851

References

• Summaries
  All 40

  Developmental Gene Expression 2

  Phenotypes 8
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208