Zfa-ps MGI Mouse Pseudogene Detail - MGI:99153 - zinc finger protein, autosomal, pseudogene

Symbol

Zfa-ps
Name

zinc finger protein, autosomal, pseudogene
Synonyms

Zfa

Feature Type

pseudogene
IDs

MGI:99153
NCBI Gene: 22639
Alliance

gene page

Sequence Map

Chr10:52419104-52421334 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 26.71 cM, cytoband B3-B4
Mapping Data

15 experiments

SNPs within 2kb

151 from dbSNP Build 142
Strain Annotations

8
RFLP

8

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_99153	pseudogene	Chr10:52418416-52421835 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0039769	pseudogene	ChrX:90464667-90485840 (-)
A/J	no annotation
AKR/J	MGP_AKRJ_G0039576	pseudogene	Chr10:51153325-51160600 (-)
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0036924	pseudogene	ChrX:88718772-88738594 (-)
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	MGP_FVBNJ_G0039404	pseudogene	Chr10:48935184-48943023 (-)
LP/J	MGP_LPJ_G0035805	pseudogene	ChrX:91252000-91272312 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0040282	pseudogene	Chr10:51066447-51070409 (-)
PWK/PhJ	MGP_PWKPhJ_G0038194	pseudogene	ChrX:73285336-73305693 (-)
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

ZFX, zinc finger protein X-linked

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZFX, zinc finger protein X-linked
Synonyms

MRXS37, ZNF926
Links

HGNC:12869

NCBI Gene ID: 7543

UniProt: P17010
Chr Location

Xp22.11; chrX:24148982-24216255 (+) GRCh38

Human Ortholog

ZFY, zinc finger protein Y-linked
Synonyms

ZNF911
Links

HGNC:12870

NCBI Gene ID: 7544

UniProt: P08048
Chr Location

Yp11.2; chrY:2935281-2982506 (+) GRCh38

MGI Vertebrate Homology

Zfa-ps stringent orthology
2 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ZFX, ZFY
Gene Tree

Zfa-ps

Diseases

1 with human ZFX associations

				Human Disease	Mouse Models
				syndromic X-linked intellectual disability IDs syndromic X-linked intellectual disability DOID:0060309 OMIM:PS309510

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

1 phenotype from 1 allele in 3 genetic backgrounds
8 phenotype references

All Mutations and Alleles

3
Chemically induced (other)

1
Radiation induced

1
Targeted

1
Genomic Mutations

2 involving Zfa-ps
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

22 strains or lines available

Male homozygous null were fertile and showed no spermatogenic or testicular defects.

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All GO Annotations

6
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

772
Tissues

19
cDNA Data

6
Literature Summary

2

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

15
RefSeq

1
UniProt

1
CCDS

CCDS23842.1

Ensembl

ENSMUSG00000049576 (Evidence)
NCBI Gene

22639

			Length	Strain/Species	Flank
genomic	ENSMUSG00000049576	Ensembl Gene Model \| MGI Sequence Detail	2231	C57BL/6J	± kb
transcript	ENSMUST00000180526	Ensembl \| MGI Sequence Detail	2231	Not Applicable
polypeptide	P23607	UniProt \| EBI \| MGI Sequence Detail		Not Loaded

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UniProt

1 Sequence
Protein Ontology

PR:000018244 zinc finger autosomal protein

(term hierarchy)

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All nucleic 17

Genomic 3

cDNA 8

Primer pair 2

Other 4

Microarray probesets 1

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MGD-MRK-15851

Summaries

All 42

Developmental Gene Expression 2

Gene Ontology 2

Phenotypes 8
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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