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Trgv7 Gene Detail
Summary
  • Symbol
    Trgv7
  • Name
    T cell receptor gamma, variable 7
  • Synonyms
    Tcrg-V7
  • Feature Type
    gene segment
  • IDs
    MGI:98637
    NCBI Gene: 21641
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:19362212-19362662 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 6.89 cM
Strain
Comparison
more
  • SNPs within 2kb
    45 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98637
gene segment Chr13:19362194-19362662 (+)
129S1/SvImJ MGP_129S1SvImJ_G0002510
gene segment Chr13:16285446-16285913 (+)
A/J MGP_AJ_G0002483
gene segment Chr13:16070951-16071418 (+)
AKR/J MGP_AKRJ_G0002469
gene segment Chr13:16265569-16266037 (+)
BALB/cJ MGP_BALBcJ_G0002479
gene segment Chr13:16035539-16036006 (+)
C3H/HeJ MGP_C3HHeJ_G0002456
gene segment Chr13:16388067-16388535 (+)
C57BL/6NJ MGP_C57BL6NJ_G0002604
gene segment Chr13:16985605-16986073 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002202
gene segment Chr13:14526264-14526732 (+)
CAST/EiJ MGP_CASTEiJ_G0002418
gene segment Chr13:16130377-16130844 (+)
CBA/J MGP_CBAJ_G0002447
gene segment Chr13:17549098-17549566 (+)
DBA/2J MGP_DBA2J_G0002453
gene segment Chr13:15648743-15649211 (+)
FVB/NJ MGP_FVBNJ_G0002466
gene segment Chr13:15336821-15337288 (+)
LP/J MGP_LPJ_G0002508
gene segment Chr13:16574662-16575130 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002436
gene segment Chr13:17943309-17943777 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002599
gene segment Chr13:16075658-16076126 (+)
PWK/PhJ MGP_PWKPhJ_G0002393
gene segment Chr13:15686094-15686562 (+)
SPRET/EiJ MGP_SPRETEiJ_G0002330
gene segment Chr13:15200690-15201157 (+)
WSB/EiJ MGP_WSBEiJ_G0002449
gene segment Chr13:16112159-16112626 (+)



Homology
more
  • Human Ortholog
    TRGV1, T cell receptor gamma variable 1 (non-functional)
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRGV1, T cell receptor gamma variable 1 (non-functional)
  • Synonyms
    TCRGV1, V1S1P
  • Links
    NCBI Gene ID: 6973
    UniProt: A0A0A0MS02

  • Chr Location
    7p14.1; chr7:38367586-38368169 (-)  GRCh38

  • Human Ortholog
    TRGV2, T cell receptor gamma variable 2
  • Synonyms
    TCRGV2, VIS2
  • Links
    NCBI Gene ID: 6974
    UniProt: A0A075B6R0

  • Chr Location
    7p14.1; chr7:38362864-38363518 (-)  GRCh38

  • Human Ortholog
    TRGV3, T cell receptor gamma variable 3
  • Synonyms
    TCRGV3, V1S3
  • Links
    NCBI Gene ID: 6976
    UniProt: P03979

  • Chr Location
    7p14.1; chr7:38358512-38359162 (-)  GRCh38

  • Human Ortholog
    TRGV4, T cell receptor gamma variable 4
  • Synonyms
    TCRGV4, V1S4
  • Links
    NCBI Gene ID: 6977
    UniProt: A0A0C4DH28

  • Chr Location
    7p14.1; chr7:38353715-38354517 (-)  GRCh38

  • Human Ortholog
    TRGV5, T cell receptor gamma variable 5
  • Synonyms
    TCRGV5, V1S5
  • Links
    NCBI Gene ID: 6978
    UniProt: A0A0B4J1U4

  • Chr Location
    7p14.1; chr7:38349355-38350022 (-)  GRCh38

  • Human Ortholog
    TRGV8, T cell receptor gamma variable 8
  • Synonyms
    TCRGV8, V1S8
  • Links
    NCBI Gene ID: 6982
    UniProt: A0A0C4DH27

  • Chr Location
    7p14.1; chr7:38330343-38330935 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
DNA-templated transcription
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 21641 NCBI Gene Model | MGI Sequence Detail 451 C57BL/6J ±  kb
transcript Z48594 GenBank | ENA | DDBJ | MGI Sequence Detail 305 ABL  
polypeptide A0A0A6YYE8 UniProt | EBI | MGI Sequence Detail 116 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less
  • All nucleic 7
    Genomic 3
    cDNA 3
    Other 1
Other
Accession IDs
less
MGD-MRK-14929
References
more
  • Summaries
    All 11
    Gene Ontology 1
    Phenotypes 1
  • Earliest
    J:30476 Takagaki Y, et al., T cell receptor-gamma and -delta genes preferentially utilized by adult thymocytes for the surface expression. J Immunol. 1989 Mar 15;142(6):2112-21
  • Latest
    J:327132 Reis BS, et al., TCR-Vgammadelta usage distinguishes protumor from antitumor intestinal gammadelta T cell subsets. Science. 2022 Jul 15;377(6603):276-284

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/21/2023
MGI 6.22
The Jackson Laboratory