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Trgc1 Gene Detail
Summary
  • Symbol
    Trgc1
  • Name
    T cell receptor gamma, constant 1
  • Synonyms
    Cgamma1, Gm17004, Tcrg-C1
Location &
Maps
more
  • Sequence Map
    Chr13:19398273-19400788 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 6.89 cM
Strain
Comparison
more
  • SNPs within 2kb
    279 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98625
 gene segment Chr13:19398273-19401194 (+)
129S1/SvImJ ENSMUSG00200014630
 gene segment Chr13:16625432-16628353 (+)
A/J ENSMUSG00195039195
 gene segment Chr13:15760384-15763305 (+)
AKR/J ENSMUSG00220033077
 gene segment Chr13:15677929-15680852 (+)
BALB/cJ ENSMUSG00180039187
 gene segment Chr13:16121028-16123949 (+)
C3H/HeJ ENSMUSG00175035685
 gene segment Chr13:16223076-16225997 (+)
C57BL/6NJ ENSMUSG00215029585
 gene segment Chr13:16154656-16157577 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005014552
 gene segment Chr13:16222007-16224928 (+)
CBA/J ENSMUSG00210031404
 gene segment Chr13:16077668-16080589 (+)
DBA/2J ENSMUSG00185014918
 gene segment Chr13:16779033-16781954 (+)
FVB/NJ ENSMUSG00205052911
 gene segment Chr13:15917498-15920419 (+)
JF1/MsJ ENSUMUG00000021898
 gene segment Chr13:16498537-16501460 (+)
LP/J ENSMUSG00230035625
 gene segment Chr13:26178890-26181813 (+)
NOD/ShiLtJ ENSMUSG00190025282
 gene segment Chr13:16051551-16054472 (+)
NZO/HlLtJ ENSMUSG00225032412
 gene segment Chr13:19917638-19920559 (+)
PWK/PhJ ENSLUMG00010034630
 gene segment Chr13:15485128-15488052 (+)
SPRET/EiJ ENSMSPG00010020138
 gene segment Chr13:15157868-15160842 (+)
WSB/EiJ ENSIUOG00005035391
 gene segment Chr13:15376044-15378965 (+)



Homology
more
  • Human Ortholog
    TRGC1, T cell receptor gamma constant 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRGC1, T cell receptor gamma constant 1
  • Synonyms
    C1, TCRG, TCRGC1
  • Links
    NCBI Gene ID: 6966
    UniProt: A2JGV3, P0CF51

  • Chr Location
    7p14.1; chr7:38260088-38265678 (-)  GRCh38
  • Human Ortholog
    TRGC2, T cell receptor gamma constant 2
  • Synonyms
    TCRGC2, TRGC2(2X), TRGC2(3X)
  • Links
    NCBI Gene ID: 6967
    UniProt: P03986

  • Chr Location
    7p14.1; chr7:38239580-38249572 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    2 phenotype references
Homozygous null mice lack dendritic epidermal T cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    1
  • cDNA Data
    1
  • Literature Summary
    2
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 107573 NCBI Gene Model | MGI Sequence Detail 2516 C57BL/6J ±  kb
polypeptide A0A075B5Z0 UniProt | EBI | MGI Sequence Detail 172 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR051117 T cell receptor gamma variable/constant region
Molecular
Reagents
less
  • All nucleic 12
    Genomic 4
    cDNA 7
    Other 1

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-14917, MGI:4440482, MGI:6331303
References
more
  • Summaries
    All 21
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:31508 Heilig JS, et al., Diversity of murine gamma genes and expression in fetal and adult T lymphocytes. Nature. 1986 Aug 28-Sep 3;322(6082):836-40
  • Latest
    J:153581 Uche UN, et al., Recombination signal sequence-associated restriction on TCRdelta gene rearrangement affects the development of tissue-specific gammadelta T cells. J Immunol. 2009 Oct 15;183(8):4931-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory