About   Help   FAQ
Mea1 Gene Detail
Summary
  • Symbol
    Mea1
  • Name
    male enhanced antigen 1
  • Synonyms
    Mea-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:96957
    NCBI Gene: 17256
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:46989719-46994037 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 22.90 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    195 from dbSNP Build 142
  • Strain Annotations
    17
  • RFLP
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96957
 protein coding gene Chr17:46989699-46994052 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023827
 protein coding gene Chr17:47761339-47763943 (+)
A/J MGP_AJ_G0023785
 protein coding gene Chr17:46613627-46616651 (+)
AKR/J MGP_AKRJ_G0023756
 protein coding gene Chr17:46958782-46963445 (+)
BALB/cJ MGP_BALBcJ_G0023789
 protein coding gene Chr17:46514063-46516865 (+)
C3H/HeJ MGP_C3HHeJ_G0023552
 protein coding gene Chr17:47704885-47707437 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024232
 protein coding gene Chr17:49810637-49813070 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021682
 protein coding gene Chr17:43395358-43397165 (+)
CAST/EiJ MGP_CASTEiJ_G0023035
 protein coding gene Chr17:47792577-47794330 (+)
CBA/J MGP_CBAJ_G0023529
 protein coding gene Chr17:51603947-51612103 (+)
DBA/2J MGP_DBA2J_G0023655
 protein coding gene Chr17:45384125-45386030 (+)
FVB/NJ MGP_FVBNJ_G0023622
 protein coding gene Chr17:45007142-45009055 (+)
LP/J MGP_LPJ_G0023736
 protein coding gene Chr17:48440322-48442109 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023651
 protein coding gene Chr17:51148676-51151203 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024277
 protein coding gene Chr17:47312443-47315274 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0022594
 protein coding gene Chr17:44182262-44187267 (+)
WSB/EiJ MGP_WSBEiJ_G0023099
 protein coding gene Chr17:47866100-47869978 (+)



Homology
more
  • Human Ortholog
    MEA1, male-enhanced antigen 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MEA1, male-enhanced antigen 1
  • Synonyms
    HYS, MEA
  • Links
    NCBI Gene ID: 4201
    UniProt: Q16626

  • Chr Location
    6p21.1; chr6:43011143-43016886 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    844
  • Tissues
    45
  • cDNA Data
    17
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002768 Ensembl Gene Model | MGI Sequence Detail 4319 C57BL/6J ±  kb
transcript ENSMUST00000233612 Ensembl | MGI Sequence Detail 766 Not Applicable  
polypeptide ENSMUSP00000156967 Ensembl | MGI Sequence Detail 174 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 17
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-12183, MGD-MRK-12185
References
more
  • Summaries
    All 27
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:10091 Lau YF, et al., Male-enhanced antigen gene is phylogenetically conserved and expressed at late stages of spermatogenesis. Proc Natl Acad Sci U S A. 1989 Nov;86(21):8462-6
  • Latest
    J:338083 Hwang I, et al., Cerebellar dysfunction and schizophrenia-like behavior in Ebp1-deficient mice. Mol Psychiatry. 2022 Apr;27(4):2030-2041
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory