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Mcpt2 Gene Detail
Summary
  • Symbol
    Mcpt2
  • Name
    mast cell protease 2
  • Synonyms
    Mcp-2, MMCP-2, MMCP-2
Location &
Maps
more
  • Sequence Map
    Chr14:56279498-56282099 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.19 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    223 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96938
 protein coding gene Chr14:56259041-56282099 (+)
129S1/SvImJ ENSMUSG00200040697
 protein coding gene Chr14:44867279-44869880 (+)
A/J ENSMUSG00195031431
 protein coding gene Chr14:45084025-45086626 (+)
AKR/J ENSMUSG00220024549
 protein coding gene Chr14:44411887-44414488 (+)
BALB/cJ ENSMUSG00180047532
 protein coding gene Chr14:44707704-44710305 (+)
C3H/HeJ ENSMUSG00175046239
 protein coding gene Chr14:46390025-46392626 (+)
C57BL/6NJ ENSMUSG00215047139
 protein coding gene Chr14:44602777-44605378 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005045903
 protein coding gene Chr14:46376750-46379351 (+)
CBA/J ENSMUSG00210044207
 protein coding gene Chr14:45070584-45073185 (+)
DBA/2J ENSMUSG00185052407
 protein coding gene Chr14:50184026-50186627 (+)
FVB/NJ ENSMUSG00205037174
 protein coding gene Chr14:44473389-44475990 (+)
JF1/MsJ ENSUMUG00000035796
 protein coding gene Chr14:61364298-61366899 (+)
LP/J ENSMUSG00230051696
 protein coding gene Chr14:62233119-62235720 (+)
NOD/ShiLtJ ENSMUSG00190045480
 protein coding gene Chr14:44836740-44839341 (+)
NZO/HlLtJ ENSMUSG00225045857
 protein coding gene Chr14:52523472-52526073 (+)
PWK/PhJ ENSLUMG00010040050
 protein coding gene Chr14:44293197-44295798 (+)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005040688
 protein coding gene Chr14:44268586-44271187 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    52
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022226 Ensembl Gene Model | MGI Sequence Detail 2602 C57BL/6J ±  kb
transcript ENSMUST00000015576 Ensembl | MGI Sequence Detail 1061 Not Applicable  
polypeptide ENSMUSP00000015576 Ensembl | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    Genomic 5
    cDNA 52

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-12144, MGD-MRK-12152
References
more
  • Summaries
    All 39
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:10169 Serafin WE, et al., Identification and molecular cloning of a novel mouse mucosal mast cell serine protease. J Biol Chem. 1990 Jan 5;265(1):423-9
  • Latest
    J:287176 Kasakura K, et al., Cooperative Regulation of the Mucosal Mast Cell-Specific Protease Genes Mcpt1 and Mcpt2 by GATA and Smad Transcription Factors. J Immunol. 2020 Mar 15;204(6):1641-1649
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory