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Ipp Gene Detail
Summary
  • Symbol
    Ipp
  • Name
    IAP promoted placental gene
  • Synonyms
    D4Jhu8, Mipp
  • Feature Type
    protein coding gene
  • IDs
    MGI:96581
    NCBI Gene: 16351
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:116364746-116395440 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 53.20 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    756 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96581
protein coding gene Chr4:116364710-116400607 (+)
129S1/SvImJ ENSMUSG00200048037
protein coding gene Chr4:110261000-110291691 (+)
A/J ENSMUSG00195046297
protein coding gene Chr4:111532473-111563063 (+)
AKR/J ENSMUSG00220010643
protein coding gene Chr4:110872950-110905928 (+)
BALB/cJ ENSMUSG00180040146
protein coding gene Chr4:109605021-109636176 (+)
C3H/HeJ ENSMUSG00175039039
protein coding gene Chr4:110619489-110650600 (+)
C57BL/6NJ ENSMUSG00215031451
protein coding gene Chr4:111688896-111719633 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026332
protein coding gene Chr4:106949302-106981695 (+)
CAST/EiJ ENSTCUG00005019355
protein coding gene Chr4:110386438-110419039 (+)
CBA/J ENSMUSG00210052968
protein coding gene Chr4:110232970-110264079 (+)
DBA/2J ENSMUSG00185048071
protein coding gene Chr4:111758155-111788730 (+)
FVB/NJ ENSMUSG00205042210
protein coding gene Chr4:109702561-109733643 (+)
JF1/MsJ ENSUMUG00000019801
protein coding gene Chr4:111657443-111690211 (+)
LP/J ENSMUSG00230045341
protein coding gene Chr4:115078291-115108972 (+)
NOD/ShiLtJ ENSMUSG00190045829
protein coding gene Chr4:109601333-109632449 (+)
NZO/HlLtJ ENSMUSG00225009810
protein coding gene Chr4:120564963-120597925 (+)
PWK/PhJ ENSLUMG00010044803
protein coding gene Chr4:109059340-109089092 (+)
SPRET/EiJ ENSMSPG00010027819
protein coding gene Chr4:111160547-111193662 (+)
WSB/EiJ ENSIUOG00005042876
protein coding gene Chr4:109920780-109951269 (+)



Homology
more
  • Human Ortholog
    IPP, intracisternal A particle-promoted polypeptide
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IPP, intracisternal A particle-promoted polypeptide
  • Synonyms
    KLHL27
  • Links
    NCBI Gene ID: 3652
    UniProt: Q9Y573

  • Chr Location
    1p34.1; chr1:45694324-45750653 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028696 Ensembl Gene Model | MGI Sequence Detail 30695 C57BL/6J ±  kb
    transcript ENSMUST00000030461 Ensembl | MGI Sequence Detail 2115 Not Applicable  
    polypeptide ENSMUSP00000030461 Ensembl | MGI Sequence Detail 584 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      Genomic 3
      cDNA 14

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-11445, MGD-MRK-12244, MGD-MRK-6591, MGI:92709
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 17
    • Earliest
      J:11287 Mold DE, et al., Cell lineage-specific expression of the MIPP gene. Biochem Biophys Res Commun. 1991 Jun 28;177(3):1062-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory