Igkv13-84 MGI Mouse Gene Detail - MGI:96514 - immunoglobulin kappa chain variable 13-84

Symbol

Igkv13-84
Name

immunoglobulin kappa chain variable 13-84
Synonyms

Igk-V33

Feature Type

gene segment
IDs

MGI:96514
NCBI Gene: 692152
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr6:68916586-68917051 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 6, 31.34 cM
Mapping Data

3 experiments

SNPs within 2kb

15 from dbSNP Build 142
Strain Annotations

12
RFLP

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_96514	gene segment	Chr6:68916586-68917051 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0000140	gene segment	Chr6:69212398-69212863 (-)
A/J	MGP_AJ_G0000133	gene segment	Chr6:66257186-66257651 (-)
AKR/J	MGP_AKRJ_G0000135	gene segment	Chr6:68134129-68134594 (+)
BALB/cJ	no annotation
C3H/HeJ	MGP_C3HHeJ_G0000122	gene segment	Chr6:115927763-115928228 (-)
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0000137	gene segment	Chr6:68520191-68520653 (+)
CBA/J	MGP_CBAJ_G0000133	gene segment	Chr6:73647502-73647967 (-)
DBA/2J	no annotation
FVB/NJ	MGP_FVBNJ_G0000125	gene segment	Chr6:65302498-65303073 (-)
LP/J	MGP_LPJ_G0000143	gene segment	Chr6:69008795-69009260 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	MGP_PWKPhJ_G0000117	gene segment	Chr6:64847933-64848398 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0000095	gene segment	Chr6:67594282-67594720 (-)
WSB/EiJ	MGP_WSBEiJ_G0000135	gene segment	Chr6:68574749-68575214 (+)

Human Ortholog

IGKV1-27, immunoglobulin kappa variable 1-27

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

IGKV1-27, immunoglobulin kappa variable 1-27
Synonyms

A20, IGKV127
Links

HGNC:5735

NCBI Gene ID: 28935

UniProt: A0A075B6S5
Chr Location

2p11.2; chr2:89213423-89213928 (-) GRCh38

Human Ortholog

IGKV1-33, immunoglobulin kappa variable 1-33
Synonyms

IGKV133, O18
Links

HGNC:5737

NCBI Gene ID: 28933
Chr Location

2p11.2; chr2:89268001-89268506 (-) GRCh38

Human Ortholog

IGKV1D-33, immunoglobulin kappa variable 1D-33
Synonyms

IGKV1D33, O8
Links

HGNC:5753

NCBI Gene ID: 28896

UniProt: P01593
Chr Location

2p11.2; chr2:89913982-89914545 (+) GRCh38

MGI Vertebrate Homology

Igkv13-84 stringent orthology
3 human;1 mouse;1 zebrafish
HCOP

vertebrate homology predictions: IGKV1-27, IGKV1-33, IGKV1D-33
Gene Tree

Igkv13-84

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Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

12 strains or lines available

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All GO Annotations

3
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

1

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

22
RefSeq

1
UniProt

1

Ensembl

ENSMUSG00000076538 (Evidence)
NCBI Gene

692152

			Length	Strain/Species	Flank
genomic	692152	NCBI Gene Model \| MGI Sequence Detail	466	C57BL/6J	± kb
transcript	M35157	GenBank \| ENA \| DDBJ \| MGI Sequence Detail	405	Not Specified
polypeptide	A0A140T8N3	UniProt \| EBI \| MGI Sequence Detail	115	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR007110 Immunoglobulin-like domain

IPR036179 Immunoglobulin-like domain superfamily

IPR013783 Immunoglobulin-like fold

IPR003599 Immunoglobulin subtype

IPR013106 Immunoglobulin V-set domain

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All nucleic 17

Genomic 7

cDNA 2

Primer pair 1

Other 7

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MGD-MRK-11317

Summaries

All 13

Gene Ontology 1
Earliest

J:10769 D'Hoostelaere LA, et al., Characterization of new mouse V kappa groups. J Immunol. 1990 Oct 15;145(8):2706-12
Latest

J:55926 Isobe T, et al., F. Genetic Strains Research Center. Analysis of the genetic structure of Pb hotspot in the Class II of MHC. Natl Inst Genet Jpn Annual Report. 1997;48:87-101

TSS for Igkv13-84:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr56931	Chr6:68916540-68916569 (+)	-31 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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