H2-Q3 Pseudogene Detail

Summary

• Symbol
  H2-Q3
• Name
  histocompatibility 2, Q region locus 3
• Synonyms
  Qa3

• Feature Type
  pseudogene
• IDs
  MGI:95932
  NCBI Gene: 625285
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr17:35577965-35578948 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 18.64 cM, cytoband B-C
• Mapping Data
  8 experiments

Strain
Comparison

• SNPs within 2kb
  1 from dbSNP Build 142
• Strain Annotations
  17

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_95932	pseudogene	Chr17:35577945-35578958 (+)
129S1/SvImJ	ENSMUSG00200052113	pseudogene	Chr17:31282091-31283074 (+)
A/J	ENSMUSG00195047833	pseudogene	Chr17:32348763-32349057 (+)
AKR/J	ENSMUSG00220052870	pseudogene	Chr17:31209693-31209874 (+)
BALB/cJ	ENSMUSG00180046160	pseudogene	Chr17:31718583-31718877 (+)
C3H/HeJ	ENSMUSG00175044611	pseudogene	Chr17:31095798-31095979 (+)
C57BL/6NJ	ENSMUSG00215053808	pseudogene	Chr17:31122332-31123315 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005052340	pseudogene	Chr17:32202085-32202138 (+)
CBA/J	ENSMUSG00210052686	pseudogene	Chr17:30917893-30918074 (+)
DBA/2J	ENSMUSG00185055425	pseudogene	Chr17:33737782-33738076 (+)
FVB/NJ	ENSMUSG00205053841	pseudogene	Chr17:31431440-31431734 (+)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230054722	pseudogene	Chr17:34680318-34681301 (+)
NOD/ShiLtJ	ENSMUSG00190053624	pseudogene	Chr17:31040887-31041870 (+)
NZO/HlLtJ	ENSMUSG00225055038	pseudogene	Chr17:36735421-36736407 (+)
PWK/PhJ	ENSLUMG00010043747	pseudogene	Chr17:30735812-30736106 (+)
SPRET/EiJ	ENSMSPG00010050916	pseudogene	Chr17:31918461-31919156 (+)
WSB/EiJ	ENSIUOG00005052252	pseudogene	Chr17:31870263-31870557 (+)

Homology

• Gene Tree
  H2-Q3
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Targeted
  1
• Genomic Mutations
  1 involving H2-Q3
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  4 strains or lines available

This locus controls a serologically detected antigen limited predominantly Thy1+ cells of lymph node and spleen. The a allele determines presence of antigen in BALB/cJ, C56BL/6, and A; the b allele determines absence of antigen in DBA/1 and SWR.

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  21
• RefSeq
  1

• Ensembl
  ENSMUSG00000092253 (Evidence)
• NCBI Gene
  625285

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000092253	Ensembl Gene Model | MGI Sequence Detail	984	C57BL/6J
transcript	ENSMUST00000172583	Ensembl | MGI Sequence Detail	608	Not Applicable

Molecular
Reagents

• All nucleic 5

  Genomic 4

  Other 1

Other
Accession IDs

MGD-MRK-10415, MGD-MRK-10528, MGD-MRK-13711, MGD-MRK-13722, MGI:3644098

References

• Summaries
  All 20

  Phenotypes 1
• Earliest
  J:4437 Flaherty L, et al., Further seriological analysis of the Qa antigens: analysis of an anti-H-2.28 serum. Immunogenetics. 1978;6:245-251
• Latest
  J:190754 Ermakova O, et al., Construction and phenotypic analysis of mice carrying a duplication of the major histocompatibility class I (MHC-I) locus. Mamm Genome. 2012 Aug;23(7-8):443-53

TSS for H2-Q3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr144360	Chr17:35577945-35577965 (+)	-10 bp