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H2-M1 Gene Detail
Summary
  • Symbol
    H2-M1
  • Name
    histocompatibility 2, M region locus 1
  • Synonyms
    H-2M1, Mb1
Location &
Maps
more
  • Sequence Map
    Chr17:36980900-36983111 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.16 cM
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • Strain Annotations
    15
  • RFLP
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95913
 protein coding gene Chr17:36979922-36983111 (-)
129S1/SvImJ ENSMUSG00200049032
 protein coding gene Chr17:32449023-32451235 (-)
A/J ENSMUSG00195041541
 protein coding gene Chr17:33651103-33653315 (-)
AKR/J no annotation
BALB/cJ ENSMUSG00180032171
 protein coding gene Chr17:33122638-33124849 (-)
C3H/HeJ no annotation
C57BL/6NJ ENSMUSG00215051055
 protein coding gene Chr17:32279209-32281420 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005051111
 protein coding gene Chr17:33518274-33520486 (-)
CBA/J no annotation
DBA/2J ENSMUSG00185042975
 protein coding gene Chr17:35103606-35105817 (-)
FVB/NJ ENSMUSG00205033760
 protein coding gene Chr17:32708039-32710251 (-)
JF1/MsJ ENSUMUG00000044354
 protein coding gene Chr17:34060013-34062225 (-)
LP/J ENSMUSG00230054083
 protein coding gene Chr17:36243911-36246123 (-)
NOD/ShiLtJ ENSMUSG00190031668
 protein coding gene Chr17:32326322-32328534 (-)
NZO/HlLtJ ENSMUSG00225052947
 protein coding gene Chr17:38193319-38195531 (-)
PWK/PhJ ENSLUMG00010035343
 protein coding gene Chr17:31937862-31940074 (-)
SPRET/EiJ ENSMSPG00010035919
 protein coding gene Chr17:33214761-33216968 (-)
WSB/EiJ ENSIUOG00005048119
 protein coding gene Chr17:33239848-33242060 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    12
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037334 Ensembl Gene Model | MGI Sequence Detail 2212 C57BL/6J ±  kb
transcript ENSMUST00000041662 Ensembl | MGI Sequence Detail 1057 Not Applicable  
polypeptide ENSMUSP00000040435 Ensembl | MGI Sequence Detail 344 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR050208 Antigen-presenting and immune regulatory MHC class I-related
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
    IPR037055 MHC class I-like antigen recognition-like superfamily
Molecular
Reagents
less
  • All nucleic 11
    Genomic 6
    cDNA 2
    Primer pair 1
    Other 2

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-10398, MGD-MRK-10509, MGD-MRK-12123
References
more
  • Summaries
    All 33
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:9208 Singer DS, et al., Characterization of a new subfamily of class I genes in the H-2 complex of the mouse. Immunogenetics. 1988;28(1):13-21
  • Latest
    J:207447 Leinders-Zufall T, et al., A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons. J Neurosci. 2014 Apr 9;34(15):5121-33
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory