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Ctla2a Gene Detail
Summary
  • Symbol
    Ctla2a
  • Name
    cytotoxic T lymphocyte-associated protein 2 alpha
  • Synonyms
    Ctla-2a
  • Feature Type
    protein coding gene
  • IDs
    MGI:88554
    NCBI Gene: 13024
  • Member of
    Ctla2 cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:61081969-61084439 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 32.56 cM, cytoband B-C1
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    142 from dbSNP Build 142
  • Strain Annotations
    15
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88554
 protein coding gene Chr13:61081969-61084439 (-)
129S1/SvImJ ENSMUSG00200015551
 protein coding gene Chr13:58018984-58021454 (-)
A/J ENSMUSG00195042672
 protein coding gene Chr13:57476451-57478921 (-)
AKR/J ENSMUSG00220040079
 protein coding gene Chr13:56984552-56987022 (-)
BALB/cJ ENSMUSG00180014219
 protein coding gene Chr13:57695958-57698428 (-)
C3H/HeJ ENSMUSG00175033277
 protein coding gene Chr13:57482040-57484510 (-)
C57BL/6NJ ENSMUSG00215032140
 protein coding gene Chr13:57489745-57492215 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018620
 protein coding gene Chr13:56252602-56254470 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210035146
 protein coding gene Chr13:57686862-57689332 (-)
DBA/2J ENSMUSG00185016390
 protein coding gene Chr13:58529953-58532423 (-)
FVB/NJ ENSMUSG00205026291
 protein coding gene Chr13:57302321-57304794 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230027052
 protein coding gene Chr13:67891835-67894305 (-)
NOD/ShiLtJ ENSMUSG00190023218
 protein coding gene Chr13:57545813-57548283 (-)
NZO/HlLtJ ENSMUSG00225046846
 protein coding gene Chr13:61585996-61588466 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010034461
 protein coding gene Chr13:57240197-57242646 (-)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Genomic Mutations
    1 involving Ctla2a
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    724
  • Tissues
    39
  • cDNA Data
    137
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13024 NCBI Gene Model | MGI Sequence Detail 2471 C57BL/6J ±  kb
transcript NM_007796 RefSeq | MGI Sequence Detail 1373 ZRU/MplStud  
polypeptide P12399 UniProt | EBI | MGI Sequence Detail 137 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 141
    Genomic 1
    cDNA 138
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-2221, MGD-MRK-2231
References
more
  • Summaries
    All 44
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory