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Cryz Gene Detail
Summary
  • Symbol
    Cryz
  • Name
    crystallin, zeta
  • Synonyms
    quinone reductase, Sez9, SEZ9
  • Feature Type
    protein coding gene
  • IDs
    MGI:88527
    NCBI Gene: 12972
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:154302348-154328819 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 79.25 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    779 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88527
protein coding gene Chr3:154302348-154328819 (+)
129S1/SvImJ ENSMUSG00200003460
protein coding gene Chr3:151272747-151299646 (+)
A/J ENSMUSG00195003328
protein coding gene Chr3:151388939-151415773 (+)
AKR/J ENSMUSG00220000315
protein coding gene Chr3:149797562-149824469 (+)
BALB/cJ ENSMUSG00180024836
protein coding gene Chr3:151240812-151267648 (+)
C3H/HeJ ENSMUSG00175018743
protein coding gene Chr3:150857414-150884244 (+)
C57BL/6NJ ENSMUSG00215010829
protein coding gene Chr3:151501400-151528306 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025756
protein coding gene Chr3:147584381-147608997 (+)
CAST/EiJ ENSTCUG00005001138
protein coding gene Chr3:151920771-151947581 (+)
CBA/J ENSMUSG00210004362
protein coding gene Chr3:151498436-151525342 (+)
DBA/2J ENSMUSG00185000061
protein coding gene Chr3:152126958-152153792 (+)
FVB/NJ ENSMUSG00205008350
protein coding gene Chr3:150428668-150455536 (+)
JF1/MsJ ENSUMUG00000023424
protein coding gene Chr3:150886750-150913197 (+)
LP/J ENSMUSG00230009222
protein coding gene Chr3:154021762-154048658 (+)
NOD/ShiLtJ ENSMUSG00190004070
protein coding gene Chr3:152480605-152507445 (+)
NZO/HlLtJ ENSMUSG00225005109
protein coding gene Chr3:156521570-156548402 (+)
PWK/PhJ ENSLUMG00010001692
protein coding gene Chr3:150827369-150853939 (+)
SPRET/EiJ ENSMSPG00010000280
protein coding gene Chr3:152147963-152176437 (+)
WSB/EiJ ENSIUOG00005015316
protein coding gene Chr3:151601671-151628526 (+)



Homology
more
  • Human Ortholog
    CRYZ, crystallin zeta
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CRYZ, crystallin zeta
  • Links
    NCBI Gene ID: 1429
    UniProt: Q08257

  • Chr Location
    1p31.1; chr1:74701488-74733104 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12972 NCBI Gene Model | MGI Sequence Detail 26472 C57BL/6J ±  kb
transcript NM_009968 RefSeq | MGI Sequence Detail 2519 C57BL/6  
polypeptide P47199 UniProt | EBI | MGI Sequence Detail 331 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 115
    Genomic 3
    cDNA 112

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-2182
References
more
  • Summaries
    All 48
    Developmental Gene Expression 1
    Gene Ontology 12
    Phenotypes 7
  • Earliest
    J:20118 Wistow G, et al., Recruitment of enzymes as lens structural proteins. Science. 1987 Jun 19;236(4808):1554-6
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory