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C8g Gene Detail
Summary
  • Symbol
    C8g
  • Name
    complement component 8, gamma polypeptide
  • Synonyms
    1700013L23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:88237
    NCBI Gene: 69379
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:25388663-25391731 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 17.31 cM, cytoband A3
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    151 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    3
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88237
 protein coding gene Chr2:25388662-25391731 (-)
129S1/SvImJ ENSMUSG00200051102
 protein coding gene Chr2:22372818-22375887 (-)
A/J ENSMUSG00195043314
 protein coding gene Chr2:22462900-22465973 (-)
AKR/J ENSMUSG00220050512
 protein coding gene Chr2:22580726-22583798 (-)
BALB/cJ ENSMUSG00180054226
 protein coding gene Chr2:22474461-22477531 (-)
C3H/HeJ ENSMUSG00175051918
 protein coding gene Chr2:22438614-22441684 (-)
C57BL/6NJ ENSMUSG00215046544
 protein coding gene Chr2:22497345-22500415 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023279
 protein coding gene Chr2:21396264-21399311 (-)
CAST/EiJ ENSTCUG00005050744
 protein coding gene Chr2:22223294-22226352 (-)
CBA/J ENSMUSG00210016498
 protein coding gene Chr2:22477597-22480666 (-)
DBA/2J ENSMUSG00185050963
 protein coding gene Chr2:22377100-22380172 (-)
FVB/NJ ENSMUSG00205049066
 protein coding gene Chr2:22231437-22234513 (-)
JF1/MsJ ENSUMUG00000024300
 protein coding gene Chr2:22292387-22295443 (-)
LP/J ENSMUSG00230038738
 protein coding gene Chr2:24308805-24311874 (-)
NOD/ShiLtJ ENSMUSG00190044164
 protein coding gene Chr2:22467966-22471037 (-)
NZO/HlLtJ ENSMUSG00225009819
 protein coding gene Chr2:32059231-32062299 (-)
PWK/PhJ ENSLUMG00010048668
 protein coding gene Chr2:22389757-22392813 (-)
SPRET/EiJ ENSMSPG00010033484
 protein coding gene Chr2:23076576-23079637 (-)
WSB/EiJ ENSIUOG00005052476
 protein coding gene Chr2:22335218-22338289 (-)



Homology
more
  • Human Ortholog
    C8G, complement C8 gamma chain
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C8G, complement C8 gamma chain
  • Synonyms
    C8C
  • Links
    NCBI Gene ID: 733
    UniProt: P07360

  • Chr Location
    9q34.3; chr9:136944870-136946980 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    621
  • Tissues
    1
  • cDNA Data
    55
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015083 Ensembl Gene Model | MGI Sequence Detail 3069 C57BL/6J ±  kb
transcript ENSMUST00000040042 Ensembl | MGI Sequence Detail 1150 Not Applicable  
polypeptide ENSMUSP00000041855 Ensembl | MGI Sequence Detail 202 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    cDNA 57
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-1715, MGI:1916629
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 9
  • Earliest
    J:11178 Spies T, et al., Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter [see comments]. Nature. 1991 May 23;351(6324):323-4
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory