Gm54583 Gene Detail

Summary

• Symbol
  Gm54583
• Name
  predicted gene, 54583

• Feature Type
  miRNA gene
• IDs
  MGI:6845644
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr16:93970161-93970270 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  22 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_6845644	miRNA gene	Chr16:93970161-93970270 (-)
129S1/SvImJ	ENSMUSG00200038487	miRNA gene	Chr16:90901620-90901729 (-)
A/J	ENSMUSG00195029521	miRNA gene	Chr16:90659393-90659502 (-)
AKR/J	ENSMUSG00220016213	miRNA gene	Chr16:90904694-90904803 (-)
BALB/cJ	ENSMUSG00180015858	miRNA gene	Chr16:90733377-90733486 (-)
C3H/HeJ	ENSMUSG00175017121	miRNA gene	Chr16:91070499-91070608 (-)
C57BL/6NJ	ENSMUSG00215035822	miRNA gene	Chr16:90862012-90862121 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005020784	miRNA gene	Chr16:90458424-90458528 (-)
CBA/J	ENSMUSG00210043250	miRNA gene	Chr16:90978017-90978126 (-)
DBA/2J	ENSMUSG00185036600	miRNA gene	Chr16:90917423-90917532 (-)
FVB/NJ	ENSMUSG00205026219	miRNA gene	Chr16:90696974-90697083 (-)
JF1/MsJ	ENSUMUG00000044379	miRNA gene	Chr16:91064201-91064310 (-)
LP/J	ENSMUSG00230028279	miRNA gene	Chr16:93448219-93448328 (-)
NOD/ShiLtJ	ENSMUSG00190028573	miRNA gene	Chr16:90885939-90886048 (-)
NZO/HlLtJ	ENSMUSG00225031629	miRNA gene	Chr16:96563746-96563855 (-)
PWK/PhJ	ENSLUMG00010014004	miRNA gene	Chr16:90702993-90703102 (-)
SPRET/EiJ	ENSMSPG00010021645	miRNA gene	Chr16:91826863-91826972 (-)
WSB/EiJ	ENSIUOG00005021443	miRNA gene	Chr16:90824043-90824152 (-)

Homology

• Gene Tree
  Gm54583
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Genomic Mutations
  1 involving Gm54583
• Find Mice (IMSR)
  0 strains or lines available

Sequences &
Gene Models

• All Sequences
  20

• Ensembl
  ENSMUSG00002075382 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00002075382	Ensembl Gene Model | MGI Sequence Detail	110	C57BL/6J
transcript	ENSMUST00020182709	Ensembl | MGI Sequence Detail	110	Not Applicable

References

• Summaries
  All 3

  Phenotypes 2
• Earliest
  J:343786 Lana-Elola E, et al., Congenital heart defects in Down syndrome are caused by increased dosage of DYRK1A. bioRxiv. 2023;
• Latest
  J:345472 Lana-Elola E, et al., Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Sci Transl Med. 2024 Jan 24;16(731):eadd6883