Gm49953 Gene Detail

Summary

• Symbol
  Gm49953
• Name
  predicted gene, 49953

• Feature Type
  lncRNA gene
• IDs
  MGI:6270673
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr16:95898376-95916431 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  57 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_6270673	lncRNA gene	Chr16:95898376-95916431 (+)
129S1/SvImJ	ENSMUSG00200016721	lncRNA gene	Chr16:92830359-92848323 (+)
A/J	ENSMUSG00195016516	lncRNA gene	Chr16:92588732-92606700 (+)
AKR/J	ENSMUSG00220009724	lncRNA gene	Chr16:92838034-92855997 (+)
BALB/cJ	ENSMUSG00180001239	lncRNA gene	Chr16:92662873-92680834 (+)
C3H/HeJ	ENSMUSG00175002956	lncRNA gene	Chr16:92999674-93017637 (+)
C57BL/6NJ	ENSMUSG00215020672	lncRNA gene	Chr16:92804339-92822300 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005012714	lncRNA gene	Chr16:92385871-92403363 (+)
CBA/J	ENSMUSG00210018003	lncRNA gene	Chr16:92902580-92921057 (+)
DBA/2J	ENSMUSG00185003551	lncRNA gene	Chr16:92846575-92864538 (+)
FVB/NJ	ENSMUSG00205015748	lncRNA gene	Chr16:92621227-92639711 (+)
JF1/MsJ	ENSUMUG00000018646	lncRNA gene	Chr16:92966355-92984049 (+)
LP/J	ENSMUSG00230028296	lncRNA gene	Chr16:95376845-95394808 (+)
NOD/ShiLtJ	ENSMUSG00190003919	lncRNA gene	Chr16:92808612-92827092 (+)
NZO/HlLtJ	ENSMUSG00225031638	lncRNA gene	Chr16:98480881-98499374 (+)
PWK/PhJ	ENSLUMG00010014910	lncRNA gene	Chr16:92619459-92637134 (+)
SPRET/EiJ	ENSMSPG00010021097	lncRNA gene	Chr16:93727100-93744447 (+)
WSB/EiJ	ENSIUOG00005014174	lncRNA gene	Chr16:92743471-92762080 (+)

Homology

• Gene Tree
  Gm49953
  

Human Diseases

• References
  4 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  64 phenotype references
  

• All Mutations and Alleles
  3
• Gene trapped
  1
• Spontaneous
  1
• Genomic Mutations
  2 involving Gm49953
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  35

• Ensembl
  ENSMUSG00000117270 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000117270	Ensembl Gene Model | MGI Sequence Detail	18056	C57BL/6J
transcript	ENSMUST00000233834	Ensembl | MGI Sequence Detail	1524	Not Applicable

References

• Summaries
  All 65

  Diseases 4

  Phenotypes 64
• Earliest
  J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
• Latest
  J:385727 Harada K, et al., Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome. Immunology. 2026 Mar;177(3):596-612