Gm49561 Pseudogene Detail

Summary

• Symbol
  Gm49561
• Name
  predicted gene, 49561

• Feature Type
  pseudogene
• IDs
  MGI:6214949
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr16:83362415-83362791 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  148 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_6214949	pseudogene	Chr16:83362415-83362791 (+)
129S1/SvImJ	ENSMUSG00200015945	pseudogene	Chr16:80253560-80253936 (+)
A/J	ENSMUSG00195022732	pseudogene	Chr16:80021861-80022237 (+)
AKR/J	ENSMUSG00220017646	pseudogene	Chr16:80206135-80206511 (+)
BALB/cJ	ENSMUSG00180002135	pseudogene	Chr16:80099984-80100360 (+)
C3H/HeJ	ENSMUSG00175009195	pseudogene	Chr16:80398223-80398599 (+)
C57BL/6NJ	ENSMUSG00215001712	pseudogene	Chr16:80223430-80223806 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005007316	pseudogene	Chr16:79895072-79895441 (+)
CBA/J	ENSMUSG00210019980	pseudogene	Chr16:80325559-80325935 (+)
DBA/2J	ENSMUSG00185005193	pseudogene	Chr16:80260187-80260563 (+)
FVB/NJ	ENSMUSG00205014478	pseudogene	Chr16:80080344-80080720 (+)
JF1/MsJ	ENSUMUG00000014600	pseudogene	Chr16:80393066-80393442 (+)
LP/J	ENSMUSG00230035659	pseudogene	Chr16:82814323-82814699 (+)
NOD/ShiLtJ	ENSMUSG00190011250	pseudogene	Chr16:80265544-80265920 (+)
NZO/HlLtJ	ENSMUSG00225031020	pseudogene	Chr16:85959335-85959711 (+)
PWK/PhJ	ENSLUMG00010005310	pseudogene	Chr16:80029324-80029700 (+)
SPRET/EiJ	ENSMSPG00010031603	pseudogene	Chr16:81035917-81036292 (+)
WSB/EiJ	ENSIUOG00005017255	pseudogene	Chr16:80203913-80204289 (+)

Homology

• Gene Tree
  Gm49561
  

Human Diseases

• References
  6 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  372 phenotype references
  

• All Mutations and Alleles
  2
• Radiation induced
  1
• Genomic Mutations
  2 involving Gm49561
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  20

• Ensembl
  ENSMUSG00000116533 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000116533	Ensembl Gene Model | MGI Sequence Detail	377	C57BL/6J
transcript	ENSMUST00000232058	Ensembl | MGI Sequence Detail	377	Not Applicable

References

• Summaries
  All 373

  Diseases 6

  Phenotypes 372
• Earliest
  J:30229 Davisson MT, et al., Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-33
• Latest
  J:391449 Thibodeau J, et al., Loss of cystathionine-beta-synthase contributes to elevated OXPHOS, a vulnerability in Ara-C-resistant Myeloid Leukemia in Down syndrome. Biochem Pharmacol. 2026 Feb 13;247:117815