Gm49558 Pseudogene Detail

Summary

• Symbol
  Gm49558
• Name
  predicted gene, 49558

• Feature Type
  pseudogene
• IDs
  MGI:6214944
  NCBI Gene: 115488663
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr16:81589104-81590886 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  150 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_6214944	pseudogene	Chr16:81589104-81590904 (+)
129S1/SvImJ	ENSMUSG00200015930	pseudogene	Chr16:78477529-78479311 (+)
A/J	ENSMUSG00195023848	pseudogene	Chr16:78245727-78247509 (+)
AKR/J	ENSMUSG00220018010	pseudogene	Chr16:78438436-78440218 (+)
BALB/cJ	ENSMUSG00180002243	pseudogene	Chr16:78323949-78325731 (+)
C3H/HeJ	ENSMUSG00175009133	pseudogene	Chr16:78622180-78623962 (+)
C57BL/6NJ	ENSMUSG00215001672	pseudogene	Chr16:78449550-78451332 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005007712	pseudogene	Chr16:78162829-78164611 (+)
CBA/J	ENSMUSG00210020046	pseudogene	Chr16:78550037-78551819 (+)
DBA/2J	ENSMUSG00185005225	pseudogene	Chr16:78484126-78485908 (+)
FVB/NJ	ENSMUSG00205016778	pseudogene	Chr16:78320884-78322666 (+)
JF1/MsJ	ENSUMUG00000012473	pseudogene	Chr16:78614885-78616667 (+)
LP/J	ENSMUSG00230020732	pseudogene	Chr16:81038383-81040165 (+)
NOD/ShiLtJ	ENSMUSG00190011080	pseudogene	Chr16:78472666-78474448 (+)
NZO/HlLtJ	ENSMUSG00225031142	pseudogene	Chr16:84193798-84195552 (+)
PWK/PhJ	ENSLUMG00010005291	pseudogene	Chr16:78271612-78273386 (+)
SPRET/EiJ	ENSMSPG00010015352	pseudogene	Chr16:79278757-79280533 (+)
WSB/EiJ	ENSIUOG00005017403	pseudogene	Chr16:78430928-78432710 (+)

Homology

• Gene Tree
  Gm49558
  

Human Diseases

• References
  6 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  372 phenotype references
  

• All Mutations and Alleles
  2
• Radiation induced
  1
• Genomic Mutations
  2 involving Gm49558
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  21

• Ensembl
  ENSMUSG00000116803 (Evidence)
• NCBI Gene
  115488663

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000116803	Ensembl Gene Model | MGI Sequence Detail	1783	C57BL/6J
transcript	ENSMUST00000231467	Ensembl | MGI Sequence Detail	775	Not Applicable

References

• Summaries
  All 375

  Diseases 6

  Phenotypes 372
• Earliest
  J:30229 Davisson MT, et al., Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-33
• Latest
  J:391449 Thibodeau J, et al., Loss of cystathionine-beta-synthase contributes to elevated OXPHOS, a vulnerability in Ara-C-resistant Myeloid Leukemia in Down syndrome. Biochem Pharmacol. 2026 Feb 13;247:117815