Gm49421 Pseudogene Detail

Summary

• Symbol
  Gm49421
• Name
  predicted gene, 49421

• Feature Type
  pseudogene
• IDs
  MGI:6155055
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr15:82327681-82328852 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 15, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  224 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_6155055	pseudogene	Chr15:82327681-82328852 (+)
129S1/SvImJ	ENSMUSG00200053826	pseudogene	Chr15:79441396-79442567 (+)
A/J	ENSMUSG00195051537	pseudogene	Chr15:79373056-79374227 (+)
AKR/J	ENSMUSG00220053363	pseudogene	Chr15:79416227-79417398 (+)
BALB/cJ	ENSMUSG00180053513	pseudogene	Chr15:79249984-79251155 (+)
C3H/HeJ	ENSMUSG00175053293	pseudogene	Chr15:79560954-79562125 (+)
C57BL/6NJ	ENSMUSG00215053099	pseudogene	Chr15:79345274-79346445 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005047647	pseudogene	Chr15:78861853-78863032 (+)
CBA/J	ENSMUSG00210050105	pseudogene	Chr15:79336039-79337210 (+)
DBA/2J	ENSMUSG00185052179	pseudogene	Chr15:79359837-79361008 (+)
FVB/NJ	ENSMUSG00205051367	pseudogene	Chr15:79096390-79097561 (+)
JF1/MsJ	ENSUMUG00000056512	pseudogene	Chr15:78934825-78935997 (+)
LP/J	ENSMUSG00230046226	pseudogene	Chr15:82681759-82682930 (+)
NOD/ShiLtJ	ENSMUSG00190053419	pseudogene	Chr15:79353135-79354306 (+)
NZO/HlLtJ	ENSMUSG00225050416	pseudogene	Chr15:83020323-83021494 (+)
PWK/PhJ	ENSLUMG00010052274	pseudogene	Chr15:79145834-79147006 (+)
SPRET/EiJ	ENSMSPG00010051639	pseudogene	Chr15:80797606-80798777 (+)
WSB/EiJ	ENSIUOG00005050871	pseudogene	Chr15:79437728-79438899 (+)

Homology

• Gene Tree
  Gm49421
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  4
• Targeted
  4
• Genomic Mutations
  4 involving Gm49421
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  20

• Ensembl
  ENSMUSG00000116472 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000116472	Ensembl Gene Model | MGI Sequence Detail	1172	C57BL/6J
transcript	ENSMUST00000230820	Ensembl | MGI Sequence Detail	340	Not Applicable

References

• Summaries
  All 4

  Phenotypes 3
• Earliest
  J:241123 Scheer N, et al., Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines. Mol Pharmacol. 2012 Jan;81(1):63-72
• Latest
  J:286122 Henderson CJ, et al., An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials. Drug Metab Dispos. 2019 Jun;47(6):601-615