Gm46524 Pseudogene Detail

Summary

• Symbol
  Gm46524
• Name
  predicted gene, 46524

• Feature Type
  pseudogene
• IDs
  MGI:5826161
  NCBI Gene: 108168249
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr15:82422490-82422803 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 15, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  61 from dbSNP Build 142
• Strain Annotations
  16

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5826161	pseudogene	Chr15:82422490-82422807 (+)
129S1/SvImJ	ENSMUSG00200053876	pseudogene	Chr15:79536210-79536523 (+)
A/J	ENSMUSG00195051889	pseudogene	Chr15:79467869-79468182 (+)
AKR/J	ENSMUSG00220053035	pseudogene	Chr15:79511046-79511359 (+)
BALB/cJ	ENSMUSG00180053934	pseudogene	Chr15:79344801-79345114 (+)
C3H/HeJ	ENSMUSG00175053382	pseudogene	Chr15:79655766-79656079 (+)
C57BL/6NJ	ENSMUSG00215053232	pseudogene	Chr15:79440076-79440389 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	ENSMUSG00210048995	pseudogene	Chr15:79430850-79431163 (+)
DBA/2J	ENSMUSG00185052239	pseudogene	Chr15:79454645-79454958 (+)
FVB/NJ	ENSMUSG00205051233	pseudogene	Chr15:79198528-79198841 (+)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230045877	pseudogene	Chr15:82776573-82776886 (+)
NOD/ShiLtJ	ENSMUSG00190053950	pseudogene	Chr15:79447948-79448261 (+)
NZO/HlLtJ	ENSMUSG00225050253	pseudogene	Chr15:83115132-83115445 (+)
PWK/PhJ	ENSLUMG00010053133	pseudogene	Chr15:79209660-79209973 (+)
SPRET/EiJ	ENSMSPG00010050882	pseudogene	Chr15:80885891-80885948 (+)
WSB/EiJ	ENSIUOG00005050288	pseudogene	Chr15:79530358-79530671 (+)

Homology

• Gene Tree
  Gm46524
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  4
• Targeted
  4
• Genomic Mutations
  4 involving Gm46524
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  19

• Ensembl
  ENSMUSG00000116104 (Evidence)
• NCBI Gene
  108168249

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000116104	Ensembl Gene Model | MGI Sequence Detail	314	C57BL/6J
transcript	ENSMUST00000229498	Ensembl | MGI Sequence Detail	314	Not Applicable

References

• Summaries
  All 6

  Phenotypes 3
• Earliest
  J:241123 Scheer N, et al., Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines. Mol Pharmacol. 2012 Jan;81(1):63-72
• Latest
  J:286122 Henderson CJ, et al., An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials. Drug Metab Dispos. 2019 Jun;47(6):601-615