Cirpil Gene Detail

Summary

• Symbol
  Cirpil
• Name
  cardiac ischemia reperfusion associated p53 interacting lncRNA
• Synonyms
  Gm36149

• Feature Type
  lncRNA gene
• IDs
  MGI:5595308
  NCBI Gene: 102639960
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr5:111638659-111640275 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  117 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5595308	lncRNA gene	Chr5:111638659-111642637 (+)
129S1/SvImJ	ENSMUSG00200024941	lncRNA gene	Chr5:105394048-105395501 (+)
A/J	ENSMUSG00195042759	lncRNA gene	Chr5:104888508-104889961 (+)
AKR/J	ENSMUSG00220051981	lncRNA gene	Chr5:104410362-104411815 (+)
BALB/cJ	ENSMUSG00180046704	lncRNA gene	Chr5:105034938-105036391 (+)
C3H/HeJ	ENSMUSG00175047073	lncRNA gene	Chr5:107021452-107022905 (+)
C57BL/6NJ	ENSMUSG00215039240	lncRNA gene	Chr5:105036459-105037912 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005032314	lncRNA gene	Chr5:104217586-104219040 (+)
CBA/J	ENSMUSG00210046986	lncRNA gene	Chr5:105773576-105775029 (+)
DBA/2J	ENSMUSG00185049223	lncRNA gene	Chr5:108799531-108800984 (+)
FVB/NJ	ENSMUSG00205052439	lncRNA gene	Chr5:104672677-104674130 (+)
JF1/MsJ	ENSUMUG00000019608	lncRNA gene	Chr5:111650684-111652138 (+)
LP/J	ENSMUSG00230049679	lncRNA gene	Chr5:112932488-112933941 (+)
NOD/ShiLtJ	ENSMUSG00190051205	lncRNA gene	Chr5:104708785-104710238 (+)
NZO/HlLtJ	ENSMUSG00225025893	lncRNA gene	Chr5:120554356-120555809 (+)
PWK/PhJ	ENSLUMG00010040391	lncRNA gene	Chr5:103557117-103558571 (+)
SPRET/EiJ	ENSMSPG00010046047	lncRNA gene	Chr5:106821260-106822719 (+)
WSB/EiJ	ENSIUOG00005045071	lncRNA gene	Chr5:107412806-107414259 (+)

Homology

• Gene Tree
  Cirpil
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 2 alleles in 2 genetic backgrounds
  6 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Radiation induced
  1
• Transgenic
  1
• Genomic Mutations
  2 involving Cirpil
• Find Mice (IMSR)
  0 strains or lines available

Homozygous null mice show exacerbated cardiac ischemia/reperfusion injury.

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  2

• Ensembl
  ENSMUSG00000120047 (Evidence)
• NCBI Gene
  102639960

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000120047	Ensembl Gene Model | MGI Sequence Detail	1617	C57BL/6J
transcript	ENSMUST00000244312	Ensembl | MGI Sequence Detail	1484	Not Applicable

Other
Accession IDs

MGI:7528743

References

• Summaries
  All 9

  Phenotypes 6
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:339952 Jiang Y, et al., Cytoplasmic sequestration of p53 by lncRNA-CIRPILalleviates myocardial ischemia/reperfusion injury. Commun Biol. 2022 Jul 18;5(1):716

TSS for Cirpil:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr47947	Chr5:111638787-111638824 (+)	147 bp