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Lncpnky Gene Detail
Summary
  • Symbol
    Lncpnky
  • Name
    lncRNA Pou3f2 adjacent neural key regulator
  • Synonyms
    Gm30731, lnc-pou3f2, Pnky
Location &
Maps
more
  • Sequence Map
    Chr4:22490548-22493126 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5589890
 lncRNA gene Chr4:22487414-22493826 (+)
129S1/SvImJ ENSMUSG00200001326
 lncRNA gene Chr4:19188309-19190899 (+)
A/J ENSMUSG00195016832
 lncRNA gene Chr4:19667995-19670585 (+)
AKR/J ENSMUSG00220001384
 lncRNA gene Chr4:19402833-19405423 (+)
BALB/cJ ENSMUSG00180001925
 lncRNA gene Chr4:19145493-19148071 (+)
C3H/HeJ ENSMUSG00175018513
 lncRNA gene Chr4:19645712-19648297 (+)
C57BL/6NJ ENSMUSG00215011241
 lncRNA gene Chr4:19269954-19272534 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0005818
 lincRNA gene Chr4:17591847-17594341 (+)
CAST/EiJ ENSTCUG00005016456
 lncRNA gene Chr4:19253461-19256149 (+)
CBA/J ENSMUSG00210001794
 lncRNA gene Chr4:19354963-19357560 (+)
DBA/2J ENSMUSG00185001292
 lncRNA gene Chr4:19461403-19464006 (+)
FVB/NJ ENSMUSG00205001941
 lncRNA gene Chr4:18980380-18982994 (+)
JF1/MsJ ENSUMUG00000001789
 lncRNA gene Chr4:19459940-19462608 (+)
LP/J ENSMUSG00230000639
 lncRNA gene Chr4:22728341-22730933 (+)
NOD/ShiLtJ ENSMUSG00190025420
 lncRNA gene Chr4:19372468-19375058 (+)
NZO/HlLtJ ENSMUSG00225001960
 lncRNA gene Chr4:26684210-26686813 (+)
PWK/PhJ ENSLUMG00010001961
 lncRNA gene Chr4:18929017-18931598 (+)
SPRET/EiJ ENSMSPG00010013468
 lncRNA gene Chr4:19473163-19475725 (+)
WSB/EiJ ENSIUOG00005008518
 lncRNA gene Chr4:19095972-19098548 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit thin cerebral cortext at E13.5, reduced neuronal stem cell proliferation and neurons in the E13.5 cortical plate.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    602
  • Tissues
    4
  • cDNA Data
    1
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      28
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 105500046 NCBI Gene Model | MGI Sequence Detail 2579 C57BL/6J ±  kb
    transcript NR_131335 RefSeq | MGI Sequence Detail 825 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 1
      cDNA 1
    Other
    Accession IDs
    less
    MGI:8262906
    References
    more
    • Summaries
      All 8
      Developmental Gene Expression 2
      Gene Ontology 1
      Phenotypes 2
    • Earliest
      J:224225 Ramos AD, et al., The long noncoding RNA Pnky regulates neuronal differentiation of embryonic and postnatal neural stem cells. Cell Stem Cell. 2015 Apr 2;16(4):439-47
    • Latest
      J:387463 Saha P, et al., Pnky lncRNA secondary structure maps identify functional regions that control neurogenesis in neural stem cells. Cell Rep. 2026 May 28;45(6):117451
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory